FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092634429> ?p ?o ?g. }

• W2092634429 endingPage "1561" @default.
• W2092634429 startingPage "1551" @default.
• W2092634429 abstract "The tubular epithelium of the kidney is susceptible to injury from many causes, such as ischemia-reperfusion and the associated oxidative stress, nephrotoxins, inflammatory and immune disorders and many others. The outcome is often acute kidney injury, which may progress to chronic kidney disease and fibrosis. Acute kidney injury involves not only direct injury to the distal tubular (DT) and proximal tubular (PT) epithelium during and immediately following the injurious event, but the closely-associated and sometimes dysfunctional renal vascular endothelium also plays an important part in modulating the tubular epithelial injury. In comparison with the PT, the DT epithelium is less sensitive to cell death, especially after ischemic injury. It is more prone to apoptosis than necrosis when it dies, and has key paracrine and autocrine functions in secreting an array of inflammatory, reparative, and survival cytokines that include chemotactic cytokines, polypeptide growth factors, and vasoactive peptides. In a neighborly way, the cytokines and growth factors secreted by the DT epithelium may then act positively on the ischemia-sensitive PT that has receptors to many of these proteins, but may not be able to synthesize them. A more complete understanding of these cellular events will allow protection against nephron destruction, regeneration leading to re-epithelialization of the injured tubules, or prevention of progression to chronic kidney disease. This review looks at these functions in the DT epithelial cells, specifically the cells in the medullary thick ascending limb of the loop of Henle, in contrast with those of the straight segment of the PT." @default.
• W2092634429 created "2016-06-24" @default.
• W2092634429 creator A5001910883 @default.
• W2092634429 creator A5043394711 @default.
• W2092634429 date "2007-01-01" @default.
• W2092634429 modified "2023-09-27" @default.
• W2092634429 title "Distal tubular epithelial cells of the kidney: Potential support for proximal tubular cell survival after renal injury" @default.
• W2092634429 cites W1544998723 @default.
• W2092634429 cites W1922925354 @default.
• W2092634429 cites W1964129726 @default.
• W2092634429 cites W1971714938 @default.
• W2092634429 cites W1975350171 @default.
• W2092634429 cites W1978350136 @default.
• W2092634429 cites W1978616639 @default.
• W2092634429 cites W1979280816 @default.
• W2092634429 cites W1982684746 @default.
• W2092634429 cites W1984417766 @default.
• W2092634429 cites W1984507539 @default.
• W2092634429 cites W1988847595 @default.
• W2092634429 cites W1995891818 @default.
• W2092634429 cites W2003919926 @default.
• W2092634429 cites W2011647487 @default.
• W2092634429 cites W2012487082 @default.
• W2092634429 cites W2013811855 @default.
• W2092634429 cites W2017881215 @default.
• W2092634429 cites W2020915357 @default.
• W2092634429 cites W2025946146 @default.
• W2092634429 cites W2026152321 @default.
• W2092634429 cites W2027622590 @default.
• W2092634429 cites W2032491192 @default.
• W2092634429 cites W2033049359 @default.
• W2092634429 cites W2034929637 @default.
• W2092634429 cites W2041213097 @default.
• W2092634429 cites W2041430298 @default.
• W2092634429 cites W2060470848 @default.
• W2092634429 cites W2066710764 @default.
• W2092634429 cites W2076897542 @default.
• W2092634429 cites W2088767843 @default.
• W2092634429 cites W2091677273 @default.
• W2092634429 cites W2096510468 @default.
• W2092634429 cites W2097942434 @default.
• W2092634429 cites W2099974351 @default.
• W2092634429 cites W2105457928 @default.
• W2092634429 cites W2108661304 @default.
• W2092634429 cites W2112244036 @default.
• W2092634429 cites W2120895559 @default.
• W2092634429 cites W2143880941 @default.
• W2092634429 cites W2161188031 @default.
• W2092634429 cites W2168601768 @default.
• W2092634429 cites W2170100899 @default.
• W2092634429 cites W2171747560 @default.
• W2092634429 cites W2189523381 @default.
• W2092634429 cites W2274969154 @default.
• W2092634429 cites W2410223704 @default.
• W2092634429 cites W4210655045 @default.
• W2092634429 cites W4232891524 @default.
• W2092634429 doi "https://doi.org/10.1016/j.biocel.2007.04.025" @default.
• W2092634429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17590379" @default.
• W2092634429 hasPublicationYear "2007" @default.
• W2092634429 type Work @default.
• W2092634429 sameAs 2092634429 @default.
• W2092634429 citedByCount "87" @default.
• W2092634429 countsByYear W20926344292012 @default.
• W2092634429 countsByYear W20926344292013 @default.
• W2092634429 countsByYear W20926344292014 @default.
• W2092634429 countsByYear W20926344292015 @default.
• W2092634429 countsByYear W20926344292016 @default.
• W2092634429 countsByYear W20926344292017 @default.
• W2092634429 countsByYear W20926344292018 @default.
• W2092634429 countsByYear W20926344292019 @default.
• W2092634429 countsByYear W20926344292020 @default.
• W2092634429 countsByYear W20926344292021 @default.
• W2092634429 countsByYear W20926344292022 @default.
• W2092634429 countsByYear W20926344292023 @default.
• W2092634429 crossrefType "journal-article" @default.
• W2092634429 hasAuthorship W2092634429A5001910883 @default.
• W2092634429 hasAuthorship W2092634429A5043394711 @default.
• W2092634429 hasConcept C126322002 @default.
• W2092634429 hasConcept C128240485 @default.
• W2092634429 hasConcept C134018914 @default.
• W2092634429 hasConcept C142724271 @default.
• W2092634429 hasConcept C170493617 @default.
• W2092634429 hasConcept C2776844834 @default.
• W2092634429 hasConcept C2776914184 @default.
• W2092634429 hasConcept C2777350860 @default.
• W2092634429 hasConcept C2778653478 @default.
• W2092634429 hasConcept C2780091579 @default.
• W2092634429 hasConcept C2780472472 @default.
• W2092634429 hasConcept C2780559512 @default.
• W2092634429 hasConcept C2781231759 @default.
• W2092634429 hasConcept C529295009 @default.
• W2092634429 hasConcept C71924100 @default.
• W2092634429 hasConcept C7876069 @default.
• W2092634429 hasConcept C86803240 @default.
• W2092634429 hasConcept C95444343 @default.
• W2092634429 hasConceptScore W2092634429C126322002 @default.
• W2092634429 hasConceptScore W2092634429C128240485 @default.
• W2092634429 hasConceptScore W2092634429C134018914 @default.

• next