Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092649185> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2092649185 endingPage "151" @default.
- W2092649185 startingPage "145" @default.
- W2092649185 abstract "Blood purification therapies have been clinically applied to treat the cytokine-induced pathological responses. The effects of direct hemoperfusion(DHP) with a beta(2)-microglobulin (BMG) adsorption column on hypercytokinemia were investigated.A hypercytokinemia model was prepared by injecting lipopolysaccharide (LPS) into femoral veins of male Wistar rats weighing 250-400 g. The hypercytokinemic rats were connected to the DHP system using a small BMG adsorption column, and time course changes in plasma levels of inflammatory cytokines were then examined.Plasma levels of interleukins (IL) 1beta and 6 and tumor necrosis factor alpha (TNF-alpha) were found to be significantly elevated within 3 h after LPS injection in the control group that underwent extracorporeal circulation without the BMG adsorption column, whereas the increases in plasma levels of IL-6 and TNF-alpha were significantly inhibited in the group that was treated with the BMG adsorption column. The adsorption rates of cytokines with the BMG adsorption column were 20-40% for IL-1beta and IL-6 and 10-85% for TNF-alpha during treatment for 3 h.These results suggest that the systemic inflammatory response syndrome with hypercytokinemia might be treated with DHP using the BMG adsorption column." @default.
- W2092649185 created "2016-06-24" @default.
- W2092649185 creator A5009694594 @default.
- W2092649185 creator A5027578308 @default.
- W2092649185 creator A5033573982 @default.
- W2092649185 creator A5036974163 @default.
- W2092649185 creator A5059271642 @default.
- W2092649185 date "2003-01-01" @default.
- W2092649185 modified "2023-09-25" @default.
- W2092649185 title "Effects of Direct Hemoperfusion with a β<sub>2</sub>-Microglobulin Adsorption Column on Hypercytokinemia in Rats" @default.
- W2092649185 cites W1964160622 @default.
- W2092649185 cites W1975063481 @default.
- W2092649185 cites W1993269584 @default.
- W2092649185 cites W1996189090 @default.
- W2092649185 cites W1996677418 @default.
- W2092649185 cites W2001676111 @default.
- W2092649185 cites W2013521255 @default.
- W2092649185 cites W2016178552 @default.
- W2092649185 cites W2019043807 @default.
- W2092649185 cites W2080132950 @default.
- W2092649185 cites W2082561367 @default.
- W2092649185 cites W2115298783 @default.
- W2092649185 cites W2123151246 @default.
- W2092649185 cites W2265947740 @default.
- W2092649185 cites W2407480665 @default.
- W2092649185 cites W2411672630 @default.
- W2092649185 doi "https://doi.org/10.1159/000069152" @default.
- W2092649185 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12601256" @default.
- W2092649185 hasPublicationYear "2003" @default.
- W2092649185 type Work @default.
- W2092649185 sameAs 2092649185 @default.
- W2092649185 citedByCount "5" @default.
- W2092649185 countsByYear W20926491852013 @default.
- W2092649185 crossrefType "journal-article" @default.
- W2092649185 hasAuthorship W2092649185A5009694594 @default.
- W2092649185 hasAuthorship W2092649185A5027578308 @default.
- W2092649185 hasAuthorship W2092649185A5033573982 @default.
- W2092649185 hasAuthorship W2092649185A5036974163 @default.
- W2092649185 hasAuthorship W2092649185A5059271642 @default.
- W2092649185 hasConcept C126322002 @default.
- W2092649185 hasConcept C134018914 @default.
- W2092649185 hasConcept C150394285 @default.
- W2092649185 hasConcept C178790620 @default.
- W2092649185 hasConcept C17991360 @default.
- W2092649185 hasConcept C185592680 @default.
- W2092649185 hasConcept C21957315 @default.
- W2092649185 hasConcept C2778063415 @default.
- W2092649185 hasConcept C2778690821 @default.
- W2092649185 hasConcept C2778754761 @default.
- W2092649185 hasConcept C2781123077 @default.
- W2092649185 hasConcept C43617362 @default.
- W2092649185 hasConcept C71924100 @default.
- W2092649185 hasConceptScore W2092649185C126322002 @default.
- W2092649185 hasConceptScore W2092649185C134018914 @default.
- W2092649185 hasConceptScore W2092649185C150394285 @default.
- W2092649185 hasConceptScore W2092649185C178790620 @default.
- W2092649185 hasConceptScore W2092649185C17991360 @default.
- W2092649185 hasConceptScore W2092649185C185592680 @default.
- W2092649185 hasConceptScore W2092649185C21957315 @default.
- W2092649185 hasConceptScore W2092649185C2778063415 @default.
- W2092649185 hasConceptScore W2092649185C2778690821 @default.
- W2092649185 hasConceptScore W2092649185C2778754761 @default.
- W2092649185 hasConceptScore W2092649185C2781123077 @default.
- W2092649185 hasConceptScore W2092649185C43617362 @default.
- W2092649185 hasConceptScore W2092649185C71924100 @default.
- W2092649185 hasIssue "2" @default.
- W2092649185 hasLocation W20926491851 @default.
- W2092649185 hasLocation W20926491852 @default.
- W2092649185 hasOpenAccess W2092649185 @default.
- W2092649185 hasPrimaryLocation W20926491851 @default.
- W2092649185 hasRelatedWork W1786177474 @default.
- W2092649185 hasRelatedWork W1977918131 @default.
- W2092649185 hasRelatedWork W1990717759 @default.
- W2092649185 hasRelatedWork W2096284471 @default.
- W2092649185 hasRelatedWork W2145943006 @default.
- W2092649185 hasRelatedWork W2148711924 @default.
- W2092649185 hasRelatedWork W2151614054 @default.
- W2092649185 hasRelatedWork W2287752887 @default.
- W2092649185 hasRelatedWork W2748952813 @default.
- W2092649185 hasRelatedWork W3032823600 @default.
- W2092649185 hasVolume "21" @default.
- W2092649185 isParatext "false" @default.
- W2092649185 isRetracted "false" @default.
- W2092649185 magId "2092649185" @default.
- W2092649185 workType "article" @default.