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- W2092668082 abstract "Objectives: We evaluated the use of extracorporeal membrane oxygenation (ECMO) as a direct bridge to adult heart transplantation. Methods: Between 2005 and 2011, 72 patients supported with ECMO underwent cardiac transplantation (ECMO group). They were compared to 370 cardiac recipients who underwent transplantation during the same period (NoECMO group). Results: Thirty-two patients were supported with peripheral ECMO, while 40 patients were supported with central ECMO. Mean duration of support before transplantation was 11 ± 14 days. The recipient and donor characteristics were: in recipients, age 50 (ECMO) vs 42 years (NoECMO) P < 0.01; days on waiting list, 23 (ECMO) vs 126 (NoECMO), P < 0.01; prior sternotomy, 67% (ECMO) vs 22% (NoECMO), P < 0.01; preoperative ventilation, 43% (ECMO) vs 2% (NoECMO), P < 0.01; preoperative inotrope support, 67% (ECMO) vs 33% (NoECMO), P < 0.01. In donors, ischaemic time was 195 (ECMO) vs 179 (noEcMO) min, P < 0.01. Occurrence of primary graft failure and one-year mortality were 43% (ECMO) vs 22% (NoECMO), P < 0.01 and 36% (ECMO) vs 27% (NoECMO), P = 0.11. Even if overall three-year survival was lower in the ECMO group, 57% (ECMO) vs 67% (NoECMO), P < 0.01, one-year conditional survival was similar in both groups, 92% at 3 years (ECMO) vs 90% at 3 years (NoECMO). Conclusions: ECMO could be used as a direct bridge for heart transplantation in adult recipients, but it is associated with increased short-term mortality. Survivors have the same life expectancy as the other transplanted patients. Further studies will be needed to compare the use of ECMO as a direct bridge for heart transplantation or for long-term mechanical circulatory support." @default.
- W2092668082 created "2016-06-24" @default.
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- W2092668082 date "2013-09-18" @default.
- W2092668082 modified "2023-09-26" @default.
- W2092668082 title "029 * EXTRACORPOREAL MEMBRANE OXYGENATION FOR BRIDGE TO HEART TRANSPLANTATION IN ADULT RECIPIENTS: SINGLE-CENTRE, SEVEN-YEAR EXPERIENCE" @default.
- W2092668082 doi "https://doi.org/10.1093/icvts/ivt372.29" @default.
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