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- W2092670749 abstract "Maternal behaviors were recorded in rats after a 4-h dam-litter separation and intracranial microinfusion of saline on Day 6 postpartum or cis-flupenthixol (FLU), a dopamine (DA) receptor antagonist, on Days 7-9, within the nucleus accumbens (NA) or dorsomedial striatum (DMS) bilaterally (5, 10, or 20 micro/microL/side), or the lateral ventricle (LV) unilaterally (20 or 40 micro/microL). The number of pups retrieved was inhibited in a dosage-dependent manner by FLU within the NA, but not in other sites. Pup retrieval did not occur within 5 min after 20 microg FLU in five out of nine NA dams; only in these dams did infusions include the shell region of the NA. Duration of pup licking was dose dependently decreased by FLU, the most within the NA, and to a lesser extent within the DMS. Nursing behavior in the kyphotic (upright, dorsally arched) posture, initiated in the absence of pup retrieval by placing the dam over the gathered pups, was not inhibited by intracranial FLU in any site assessed, but rather lasted longer after FLU in NA dams. These various effects of FLU, especially in NA, may be related to modest increases in catalepsy." @default.
- W2092670749 created "2016-06-24" @default.
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- W2092670749 date "1999-11-01" @default.
- W2092670749 modified "2023-10-11" @default.
- W2092670749 title "Dopamine Receptor Blockade in the Nucleus Accumbens Inhibits Maternal Retrieval and Licking, but Enhances Nursing Behavior in Lactating Rats" @default.
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- W2092670749 doi "https://doi.org/10.1016/s0031-9384(99)00116-x" @default.
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