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• W2092728601 abstract "To investigate the physiological regulatory mechanism of human atrial natriuretic polypeptide (hANP) secretion, plasma hANP was measured by a direct radioimmunoassay during head-out total body water immersion (WI) in normal men. Five healthy men were immersed in water for 1 hr. Urine volume and Na excretion were significantly increased during WI. Plasma hANP increased significantly during WI peaking at 30 min. and returned toward the baseline after WI. Plasma renin activity and norepinephrine were suppressed occasionally during WI. Plasma ADH did not change throughout the study period. Maximal increments in plasma hANP correlated with that in urine output or urinary Na excretion during WI. These data suggest that acute central hypervolemia caused by WI increases hANP secretion and that this increase may participate in the diuretic response to WI." @default.
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• W2092728601 date "1986-06-01" @default.
• W2092728601 modified "2023-10-15" @default.
• W2092728601 title "Significant increase in plasma immunoreactive atrial natriuretic polypeptide concentration during head-out water immersion" @default.
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• W2092728601 doi "https://doi.org/10.1016/0024-3205(86)90610-7" @default.
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