Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092769513> ?p ?o ?g. }
- W2092769513 endingPage "377" @default.
- W2092769513 startingPage "366" @default.
- W2092769513 abstract "Acyl-coenzyme A thioesterases (Acots) play important cellular roles in mammalian fatty acid metabolism through modulation of cellular concentrations of activated fatty acyl-CoAs. Acots catalyse the hydrolysis of the thioester bond present within acyl-CoA ester molecules to yield coenzyme A (CoASH) and the corresponding non-esterified fatty acid. Acyl-CoA thioesterases are expressed ubiquitously in both prokaryotes and eukaryotes and, in higher order organisms, the enzymes are expressed and localised in a tissue-dependent manner within the cytosol, mitochondria, peroxisomes and endoplasmic reticulum. Recent studies have led to advances in the functional and structural characterization of many mammalian Acot family members. These include the structure determination of both type-I and type-II Acot family members, structural elucidation of the START domain of ACOT11, identification of roles in arachidonic acid and inflammatory prostaglandin production by Acot7, and inclusion of a 13th Acot family member. Here, we review and analyse the current literature on mammalian Acots with respect to their characterization and summarize the current knowledge on the structure, function and regulation of this enzyme family." @default.
- W2092769513 created "2016-06-24" @default.
- W2092769513 creator A5006993794 @default.
- W2092769513 creator A5029725982 @default.
- W2092769513 creator A5048781715 @default.
- W2092769513 creator A5053221368 @default.
- W2092769513 creator A5074391037 @default.
- W2092769513 date "2010-10-01" @default.
- W2092769513 modified "2023-09-30" @default.
- W2092769513 title "Functional and structural properties of mammalian acyl-coenzyme A thioesterases" @default.
- W2092769513 cites W1487124588 @default.
- W2092769513 cites W1570847438 @default.
- W2092769513 cites W1855537617 @default.
- W2092769513 cites W1868003385 @default.
- W2092769513 cites W1969713765 @default.
- W2092769513 cites W1972050500 @default.
- W2092769513 cites W1978058114 @default.
- W2092769513 cites W1978978930 @default.
- W2092769513 cites W1982781709 @default.
- W2092769513 cites W1985415243 @default.
- W2092769513 cites W1986449189 @default.
- W2092769513 cites W1991882913 @default.
- W2092769513 cites W1992286373 @default.
- W2092769513 cites W2007002379 @default.
- W2092769513 cites W2008867070 @default.
- W2092769513 cites W2011766668 @default.
- W2092769513 cites W2016708205 @default.
- W2092769513 cites W2017205248 @default.
- W2092769513 cites W2025993358 @default.
- W2092769513 cites W2026281923 @default.
- W2092769513 cites W2033292036 @default.
- W2092769513 cites W2033738091 @default.
- W2092769513 cites W2035232572 @default.
- W2092769513 cites W2047316348 @default.
- W2092769513 cites W2047899898 @default.
- W2092769513 cites W2049968714 @default.
- W2092769513 cites W2050590566 @default.
- W2092769513 cites W2052937810 @default.
- W2092769513 cites W2056959025 @default.
- W2092769513 cites W2057477742 @default.
- W2092769513 cites W2058853260 @default.
- W2092769513 cites W2059432469 @default.
- W2092769513 cites W2061361921 @default.
- W2092769513 cites W2066845483 @default.
- W2092769513 cites W2069330160 @default.
- W2092769513 cites W2075047763 @default.
- W2092769513 cites W2082374612 @default.
- W2092769513 cites W2085085319 @default.
- W2092769513 cites W2086264391 @default.
- W2092769513 cites W2089631934 @default.
- W2092769513 cites W2090157216 @default.
- W2092769513 cites W2090764244 @default.
- W2092769513 cites W2091744486 @default.
- W2092769513 cites W2101300496 @default.
- W2092769513 cites W2106849495 @default.
- W2092769513 cites W2111938621 @default.
- W2092769513 cites W2113577869 @default.
- W2092769513 cites W2114582609 @default.
- W2092769513 cites W2121805080 @default.
- W2092769513 cites W2130109770 @default.
- W2092769513 cites W2138309115 @default.
- W2092769513 cites W2147457396 @default.
- W2092769513 cites W2149153939 @default.
- W2092769513 cites W2154766926 @default.
- W2092769513 cites W2164795094 @default.
- W2092769513 cites W2166118605 @default.
- W2092769513 cites W2167595306 @default.
- W2092769513 cites W2168254401 @default.
- W2092769513 cites W2172037414 @default.
- W2092769513 cites W2277530190 @default.
- W2092769513 cites W2601704071 @default.
- W2092769513 cites W4241224397 @default.
- W2092769513 cites W6616626 @default.
- W2092769513 doi "https://doi.org/10.1016/j.plipres.2010.04.001" @default.
- W2092769513 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20470824" @default.
- W2092769513 hasPublicationYear "2010" @default.
- W2092769513 type Work @default.
- W2092769513 sameAs 2092769513 @default.
- W2092769513 citedByCount "120" @default.
- W2092769513 countsByYear W20927695132012 @default.
- W2092769513 countsByYear W20927695132013 @default.
- W2092769513 countsByYear W20927695132014 @default.
- W2092769513 countsByYear W20927695132015 @default.
- W2092769513 countsByYear W20927695132016 @default.
- W2092769513 countsByYear W20927695132017 @default.
- W2092769513 countsByYear W20927695132018 @default.
- W2092769513 countsByYear W20927695132019 @default.
- W2092769513 countsByYear W20927695132020 @default.
- W2092769513 countsByYear W20927695132021 @default.
- W2092769513 countsByYear W20927695132022 @default.
- W2092769513 countsByYear W20927695132023 @default.
- W2092769513 crossrefType "journal-article" @default.
- W2092769513 hasAuthorship W2092769513A5006993794 @default.
- W2092769513 hasAuthorship W2092769513A5029725982 @default.
- W2092769513 hasAuthorship W2092769513A5048781715 @default.
- W2092769513 hasAuthorship W2092769513A5053221368 @default.
- W2092769513 hasAuthorship W2092769513A5074391037 @default.
- W2092769513 hasConcept C104317684 @default.