Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092828011> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2092828011 endingPage "3264" @default.
- W2092828011 startingPage "3257" @default.
- W2092828011 abstract "Dasatinib, a potent, oral kinase inhibitor, is presently approved for Philadelphia-positive chronic myelogenous leukaemia (CML) following imatinib failure. In an in vitro study, dasatinib had 325-fold greater potency than imatinib for inhibiting unmutated BCR-ABL. Phase I and II data show that dasatinib 70 mg b.i.d. is effective after imatinib failure in various phases of CML. Comparative data of dasatinib versus high-dose imatinib in patients with resistance or intolerance to imatinib demonstrated that dasatinib was associated with improved response rates and progression-free survival. Side effects of dasatinib, including pleural effusions, are manageable with modification of dose or schedule. Phase III dose optimisation studies and future indications are also discussed." @default.
- W2092828011 created "2016-06-24" @default.
- W2092828011 creator A5035964802 @default.
- W2092828011 date "2007-11-26" @default.
- W2092828011 modified "2023-10-15" @default.
- W2092828011 title "Dasatinib for the treatment of Philadelphia chromosome-positive chronic myelogenous leukaemia after imatinib failure" @default.
- W2092828011 cites W1968351802 @default.
- W2092828011 cites W1970962784 @default.
- W2092828011 cites W1978526996 @default.
- W2092828011 cites W1988399039 @default.
- W2092828011 cites W1994309500 @default.
- W2092828011 cites W2004492241 @default.
- W2092828011 cites W2026039175 @default.
- W2092828011 cites W2026395492 @default.
- W2092828011 cites W2028959752 @default.
- W2092828011 cites W2032775411 @default.
- W2092828011 cites W2061190758 @default.
- W2092828011 cites W2068840505 @default.
- W2092828011 cites W2070683532 @default.
- W2092828011 cites W2076736727 @default.
- W2092828011 cites W2079446921 @default.
- W2092828011 cites W2080125373 @default.
- W2092828011 cites W2092606584 @default.
- W2092828011 cites W2097946794 @default.
- W2092828011 cites W2100500978 @default.
- W2092828011 cites W2101635775 @default.
- W2092828011 cites W2106575058 @default.
- W2092828011 cites W2107268345 @default.
- W2092828011 cites W2112097288 @default.
- W2092828011 cites W2131171876 @default.
- W2092828011 cites W2149468947 @default.
- W2092828011 cites W2151486690 @default.
- W2092828011 cites W2171620938 @default.
- W2092828011 cites W4246110794 @default.
- W2092828011 doi "https://doi.org/10.1517/14656566.8.18.3257" @default.
- W2092828011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18035968" @default.
- W2092828011 hasPublicationYear "2007" @default.
- W2092828011 type Work @default.
- W2092828011 sameAs 2092828011 @default.
- W2092828011 citedByCount "18" @default.
- W2092828011 countsByYear W20928280112012 @default.
- W2092828011 countsByYear W20928280112015 @default.
- W2092828011 countsByYear W20928280112016 @default.
- W2092828011 countsByYear W20928280112019 @default.
- W2092828011 countsByYear W20928280112020 @default.
- W2092828011 crossrefType "journal-article" @default.
- W2092828011 hasAuthorship W2092828011A5035964802 @default.
- W2092828011 hasConcept C104317684 @default.
- W2092828011 hasConcept C126322002 @default.
- W2092828011 hasConcept C138626823 @default.
- W2092828011 hasConcept C143998085 @default.
- W2092828011 hasConcept C2776960273 @default.
- W2092828011 hasConcept C2777583451 @default.
- W2092828011 hasConcept C2778461978 @default.
- W2092828011 hasConcept C2778729363 @default.
- W2092828011 hasConcept C2778904597 @default.
- W2092828011 hasConcept C2779536868 @default.
- W2092828011 hasConcept C54355233 @default.
- W2092828011 hasConcept C71924100 @default.
- W2092828011 hasConcept C86803240 @default.
- W2092828011 hasConcept C98274493 @default.
- W2092828011 hasConceptScore W2092828011C104317684 @default.
- W2092828011 hasConceptScore W2092828011C126322002 @default.
- W2092828011 hasConceptScore W2092828011C138626823 @default.
- W2092828011 hasConceptScore W2092828011C143998085 @default.
- W2092828011 hasConceptScore W2092828011C2776960273 @default.
- W2092828011 hasConceptScore W2092828011C2777583451 @default.
- W2092828011 hasConceptScore W2092828011C2778461978 @default.
- W2092828011 hasConceptScore W2092828011C2778729363 @default.
- W2092828011 hasConceptScore W2092828011C2778904597 @default.
- W2092828011 hasConceptScore W2092828011C2779536868 @default.
- W2092828011 hasConceptScore W2092828011C54355233 @default.
- W2092828011 hasConceptScore W2092828011C71924100 @default.
- W2092828011 hasConceptScore W2092828011C86803240 @default.
- W2092828011 hasConceptScore W2092828011C98274493 @default.
- W2092828011 hasIssue "18" @default.
- W2092828011 hasLocation W20928280111 @default.
- W2092828011 hasLocation W20928280112 @default.
- W2092828011 hasOpenAccess W2092828011 @default.
- W2092828011 hasPrimaryLocation W20928280111 @default.
- W2092828011 hasRelatedWork W1983852790 @default.
- W2092828011 hasRelatedWork W1984313504 @default.
- W2092828011 hasRelatedWork W1993369250 @default.
- W2092828011 hasRelatedWork W2092828011 @default.
- W2092828011 hasRelatedWork W2112405804 @default.
- W2092828011 hasRelatedWork W2149357045 @default.
- W2092828011 hasRelatedWork W2184534421 @default.
- W2092828011 hasRelatedWork W2618548116 @default.
- W2092828011 hasRelatedWork W2941817612 @default.
- W2092828011 hasRelatedWork W4253096022 @default.
- W2092828011 hasVolume "8" @default.
- W2092828011 isParatext "false" @default.
- W2092828011 isRetracted "false" @default.
- W2092828011 magId "2092828011" @default.
- W2092828011 workType "article" @default.