Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092845901> ?p ?o ?g. }
- W2092845901 endingPage "1312" @default.
- W2092845901 startingPage "1303" @default.
- W2092845901 abstract "The production of free radicals and the resulting oxidative damage of cellular structures are always connected with the formation of oxidized proteins. The 20S proteasome is responsible for recognition and degradation of oxidatively damaged proteins. No detailed studies on the intracellular distribution of oxidized proteins during oxidative stress and on the distribution of the proteasome have been performed until now. Therefore, we used immunocytochemical methods to measure protein carbonyls, a form of protein oxidation products, and proteasome distribution within cells. Both immunocytochemical methods of measurement are semiquantitative and the load of oxidized proteins is increased after various oxidative stresses explored, with the highest increase in the perinuclear region of the cell. Distribution of the proteasome and the total protein content revealed the highest concentration of both in the nucleus. No redistribution of the proteasome during oxidative stress occurs. The normalized ratio of protein carbonyls to protein content was formed, indicating the highest concentration of oxidized proteins in the cytosolic region near the cell membrane. By forming the protein oxidation-to-proteasome ratio it was concluded that the highest load of oxidized proteins to the proteasome takes place in the cytosol, independent of the oxidant explored." @default.
- W2092845901 created "2016-06-24" @default.
- W2092845901 creator A5005155944 @default.
- W2092845901 creator A5013267759 @default.
- W2092845901 creator A5050771291 @default.
- W2092845901 creator A5083198470 @default.
- W2092845901 creator A5087695782 @default.
- W2092845901 date "2006-04-01" @default.
- W2092845901 modified "2023-10-03" @default.
- W2092845901 title "Intracellular distribution of oxidized proteins and proteasome in HT22 cells during oxidative stress" @default.
- W2092845901 cites W1508162082 @default.
- W2092845901 cites W1523840486 @default.
- W2092845901 cites W1531318383 @default.
- W2092845901 cites W1538904872 @default.
- W2092845901 cites W1551589974 @default.
- W2092845901 cites W1555938743 @default.
- W2092845901 cites W1559685509 @default.
- W2092845901 cites W1567614586 @default.
- W2092845901 cites W1573531091 @default.
- W2092845901 cites W1682982111 @default.
- W2092845901 cites W1751574485 @default.
- W2092845901 cites W190261825 @default.
- W2092845901 cites W1964376084 @default.
- W2092845901 cites W1966012405 @default.
- W2092845901 cites W1967521176 @default.
- W2092845901 cites W1972958434 @default.
- W2092845901 cites W1978839418 @default.
- W2092845901 cites W1982293936 @default.
- W2092845901 cites W1982418352 @default.
- W2092845901 cites W1991721995 @default.
- W2092845901 cites W1994946469 @default.
- W2092845901 cites W1997337854 @default.
- W2092845901 cites W2001426234 @default.
- W2092845901 cites W2003928089 @default.
- W2092845901 cites W2008744347 @default.
- W2092845901 cites W2010921067 @default.
- W2092845901 cites W2014070897 @default.
- W2092845901 cites W2014571959 @default.
- W2092845901 cites W2018970686 @default.
- W2092845901 cites W2020145725 @default.
- W2092845901 cites W2027262540 @default.
- W2092845901 cites W2034739109 @default.
- W2092845901 cites W2037116841 @default.
- W2092845901 cites W2044320834 @default.
- W2092845901 cites W2046907311 @default.
- W2092845901 cites W2049557390 @default.
- W2092845901 cites W2057491765 @default.
- W2092845901 cites W2059717037 @default.
- W2092845901 cites W2061508611 @default.
- W2092845901 cites W2061797629 @default.
- W2092845901 cites W2069749705 @default.
- W2092845901 cites W2070038654 @default.
- W2092845901 cites W2071540209 @default.
- W2092845901 cites W2071870637 @default.
- W2092845901 cites W2076510866 @default.
- W2092845901 cites W2079232374 @default.
- W2092845901 cites W2092279282 @default.
- W2092845901 cites W2094570479 @default.
- W2092845901 cites W2097336990 @default.
- W2092845901 cites W2105989455 @default.
- W2092845901 cites W2116907551 @default.
- W2092845901 cites W2117620996 @default.
- W2092845901 cites W2132195610 @default.
- W2092845901 cites W2133874291 @default.
- W2092845901 cites W2150123812 @default.
- W2092845901 cites W2150418491 @default.
- W2092845901 cites W2164066515 @default.
- W2092845901 cites W2177092266 @default.
- W2092845901 cites W2405525053 @default.
- W2092845901 cites W4211019851 @default.
- W2092845901 cites W4231065667 @default.
- W2092845901 cites W4251619131 @default.
- W2092845901 cites W66834092 @default.
- W2092845901 cites W83831086 @default.
- W2092845901 cites W946512587 @default.
- W2092845901 doi "https://doi.org/10.1016/j.freeradbiomed.2005.11.023" @default.
- W2092845901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16631520" @default.
- W2092845901 hasPublicationYear "2006" @default.
- W2092845901 type Work @default.
- W2092845901 sameAs 2092845901 @default.
- W2092845901 citedByCount "67" @default.
- W2092845901 countsByYear W20928459012012 @default.
- W2092845901 countsByYear W20928459012013 @default.
- W2092845901 countsByYear W20928459012014 @default.
- W2092845901 countsByYear W20928459012015 @default.
- W2092845901 countsByYear W20928459012016 @default.
- W2092845901 countsByYear W20928459012017 @default.
- W2092845901 countsByYear W20928459012018 @default.
- W2092845901 countsByYear W20928459012019 @default.
- W2092845901 countsByYear W20928459012020 @default.
- W2092845901 countsByYear W20928459012021 @default.
- W2092845901 countsByYear W20928459012022 @default.
- W2092845901 countsByYear W20928459012023 @default.
- W2092845901 crossrefType "journal-article" @default.
- W2092845901 hasAuthorship W2092845901A5005155944 @default.
- W2092845901 hasAuthorship W2092845901A5013267759 @default.
- W2092845901 hasAuthorship W2092845901A5050771291 @default.
- W2092845901 hasAuthorship W2092845901A5083198470 @default.