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- W2092866681 abstract "Sodium alginate (SA) and gelatine (G) based hydrogels with various SA/G ratios, crosslinked with calcium ions (Ca 2+ ) and glutaraldehyde (GTA), respectively, were developed. Scanning electron microscopy, Fourier transform infrared spectroscopy (FTIR), and dynamic mechanical analysis (DMA) were applied to determine their physicochemical characterization . The swelling studies, conducted in phosphate-buffered saline with a pH ranging from 1 to 11 at 37 °C, were utilized for an evaluation of their absorption ability. FTIR spectra of the Ca 2+ crosslinked SA/G hydrogels revealed a small shift in symmetric stretching carboxyl groups, indicating an ionic binding between the Ca 2+ ions and the SA. Increasing the G content in hydrogels crosslinked with GTA significantly changed the shapes of the amide I and II bands in the FTIR spectra, thus confirming the G–GTA crosslink formation. After crosslinking, a DMA study proved the enhanced viscoelastic properties and improved thermal stability of the prepared samples. The obtained data indicated that Ca 2+ crosslinked hydrogels with a SA/G 50/50 ratio provide a good balance of swelling and viscoelastic properties, making them applicable as a potential nontoxic wound dressing material capable of adequately assuring a moist environment , elasticity and mechanical strength for comfortable wound healing." @default.
- W2092866681 created "2016-06-24" @default.
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- W2092866681 date "2013-02-01" @default.
- W2092866681 modified "2023-10-10" @default.
- W2092866681 title "On the development and characterisation of crosslinked sodium alginate/gelatine hydrogels" @default.
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- W2092866681 doi "https://doi.org/10.1016/j.jmbbm.2012.11.010" @default.
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