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• W2092883132 abstract "Natural oils that are rich in biologically active polyunsaturated fatty acids have many health benefits. However, these natural oils have insufficient bioavailability and may oxidize in the gastrointestinal tract. For these reasons, the possibility of incorporating natural oils extracted from Siberian species, such as Baikal fish oil and Siberian cedar seed oil, and free fatty acids extracted from Baikal fish oil into pH-sensitive nano- and microparticles (Eudragit® L 100-55, S 100, L 100) was investigated. Emulsification-diffusion and precipitation methods have been used to incorporate natural oils into nano- and microparticles. The influence of parameters such as stirring speed, polymer-oil ratio, surfactant concentration and oil type was investigated. The particles were characterised in terms of their morphology, size distribution, encapsulation efficiency and pH sensitivity. The percentage of encapsulated oil ranged from 11 to 99% depending on the formulation parameters. Given the high encapsulation efficiency and pH sensitivity of the nano- and microparticles obtained, these formulations are promising systems for improving the site-specific delivery and bioavailability of bioactive oils, fatty acids and dissolved liposoluble active ingredients." @default.
• W2092883132 created "2016-06-24" @default.
• W2092883132 creator A5025087607 @default.
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• W2092883132 date "2013-09-01" @default.
• W2092883132 modified "2023-10-12" @default.
• W2092883132 title "Encapsulation of alimentary bioactive oils of the Baikal Lake area into pH-sensitive micro- and nanoparticles" @default.
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• W2092883132 doi "https://doi.org/10.1016/j.lwt.2013.01.020" @default.
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