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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2092919851> ?p ?o ?g. }

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• W2092919851 abstract "The haematological changes in early years following neonatal diagnosis have been observed in representative groups of children with sickle cell-haemoglobin C (SC) disease, sickle cell-β+ thalassaemia, and in sickle cell-β° thalassaemia. Most haematological indices in SC disease were intermediate between previously published values in SS disease and in AA controls, generally being closer to values in normal children. Exceptions were microcytosis which may be genetically determined and a striking elevation of mean cell haemoglobin concentration from age 2 months to 4 years. The combination of a raised MCHC and a lowered MCV is unusual and may be characteristic of SC disease. Features in sickle cell-β thalassaemia generally differed according to the type ofβ thalassaemia gene. Sickle cell-β° thalassaemia had lower levels of haemoglobin, MCHC, red cell count, MCV, and higher reticulocytes, most differences being significant before 1 year. No differences between Sβ° thalassaemia and Sβ+ thalassaemia were apparent in HbF levels (which resembled those in SS disease) or in HbA2 levels (which exceeded those in SS disease by 1 year of age)." @default.
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• W2092919851 date "1985-06-01" @default.
• W2092919851 modified "2023-09-23" @default.
• W2092919851 title "Haematological change in sickle cell–haemoglobin C disease and in sickle cell-beta thalassaemia: a cohort study from birth" @default.
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• W2092919851 doi "https://doi.org/10.1111/j.1365-2141.1985.tb07414.x" @default.
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