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• W2092920150 abstract "Using a uniquely promiscuous engineered glycosyltransferase (GT) derived from the macrolide-inactivating GT OleD, a single-step asymmetric glucosylation of one ‘arm’ of the drug mitoxantrone was efficiently achieved in high stereo- and regiospecificity. The synthesis, structural elucidation, and anticancer activity of the corresponding mitoxantrone 4′-β-d-glucoside are described." @default.
• W2092920150 created "2016-06-24" @default.
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• W2092920150 date "2011-04-29" @default.
• W2092920150 modified "2023-09-27" @default.
• W2092920150 title "Asymmetric Enzymatic Glycosylation of Mitoxantrone" @default.
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• W2092920150 doi "https://doi.org/10.1021/ol200977u" @default.
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