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- W2092924376 abstract "A hybrid virus containing the left half of the Ad5 genome and the right half of the Ad2 genome has been constructed by ligating together in vitro the BamHI-A fragment of Ad5 (map co-ordinates 0-59.5) to the BamHI-A fragment of Ad2 (map co-ordinates 59.5-100), and using this DNA to transfect susceptible cells. Viable progeny virus has been obtained which grows as well as the parental virus without any requirement for helper virus, and probably contains a hybrid hexon polypeptide consisting of the major part of the Ad5 hexon with an Ad2 carboxy terminus." @default.
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- W2092924376 date "1981-04-01" @default.
- W2092924376 modified "2023-09-23" @default.
- W2092924376 title "In vitro construction of a recombinant adenovirus Ad2:Ad5" @default.
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- W2092924376 doi "https://doi.org/10.1016/0378-1119(81)90035-4" @default.
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