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- W2092971319 abstract "A new series of enantiomerically pure 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines were synthesized for the first time in twelve steps from 1-fluoro-2-nitrobenzene and S-amino acids with 13–20% overall yields. First use of intramolecular Mitsunobu cyclization for 1,2,3,4-tetrahydroquinoxalines followed by PPh3/I2/imidazole mediated 6-exo-tet cyclization were the key steps." @default.
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- W2092971319 date "2010-01-01" @default.
- W2092971319 modified "2023-10-18" @default.
- W2092971319 title "A new synthesis of amino acid-based enantiomerically pure substituted 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines" @default.
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- W2092971319 doi "https://doi.org/10.1039/c000029a" @default.
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