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- W2092984593 abstract "The therapeutic strategy in systemic necrotizing vasculitides comprises steroids and, in severe forms, immunosuppressants like cyclophosphamide. A combination of steroids and immunosuppressants should be proposed for severe forms only. When factors of poor prognosis are absent, steroids alone can be prescribed. When vasculitides are related to viral infection, a specific approach is needed that comprises a combination of antiviral treatments and plasma exchanges. In Wegener's granulomatosis, the combination of steroids and cyclophosphamide, either oral or pulse, should be prescribed. A maintenance treatment with azathioprine or methotrexate is recommended. Alternative treatments using other immunosuppressants or immunomodulating agents can be prescribed in the case of relapse or in patients who do not respond to conventional treatments. The different therapeutic modalities should also be adapted to the patient's age and general condition." @default.
- W2092984593 created "2016-06-24" @default.
- W2092984593 creator A5082190748 @default.
- W2092984593 date "2001-09-01" @default.
- W2092984593 modified "2023-09-27" @default.
- W2092984593 title "Treatments for systemic vasculitides" @default.
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- W2092984593 doi "https://doi.org/10.1016/s0953-6205(01)00160-1" @default.
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