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- W2092986734 abstract "Previous lipid analysis of trichomonads has led to controversy as to whether these hydrogenosome-containing organisms contain cardiolipin (CL), which is a characteristic component of mitochondria. Here we report a careful lipid analysis of the sexually transmitted protist Trichomonas vaginalis. Major lipids were phosphatidylethanolamine (42%) and phosphatidylcholine (20%) with lesser amounts of phosphatidylglycerol (PG) (12%) and non-polar components. Two unusual lipids, acyl-PG (8%) and ceramide phosphorylethanolamine (2%), were also significant components. The structures of these lipids were confirmed by tandem mass spectrometry following reverse-phase high-performance liquid chromatography. This is the first time ceramide phosphorylethanolamine has been reported in a trichomonad. In contrast, CL (diphosphatidylglycerol) could not be detected either by two-dimensional thin-layer chromatography or by mass spectrometry. These data are discussed in relation to the organism's phylogenetic origin as a parasite showing secondary adaptation to microaerobic conditions." @default.
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- W2092986734 date "2009-01-01" @default.
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- W2092986734 title "The Microaerophilic Flagellate,<i>Trichomonas vaginalis</i>, Contains Unusual Acyl Lipids but no Detectable Cardiolipin" @default.
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- W2092986734 doi "https://doi.org/10.1111/j.1550-7408.2008.00365.x" @default.
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