FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093000550> ?p ?o ?g. }

• W2093000550 endingPage "1222" @default.
• W2093000550 startingPage "1215" @default.
• W2093000550 abstract "ObjectiveEffects of timing of inception of amiodarone antiarrhythmic treatment after corrective surgery for congenital heart defects are not yet well defined.MethodsIn a 10-year prospective observational study, 71 of 2651 patients (2885 procedures, 2106 bypass procedures) received amiodarone for newly detected postoperative atrial (n = 70) or ventricular (n = 7) tachyarrhythmia: early treatment (initiation within 60 minutes of arrhythmia detection) and late treatment (after that). From an interim analysis, a treatment protocol was established (32 patients). Inotropic requirements were monitored, as were heart rate, blood pressure, central venous pressure, and sedation requirements.ResultsWith early treatment (n = 29), delay before start of amiodarone was 40.7 ± 21.9 minutes, versus 227.7 ± 228.1 minutes (P < .001) with late treatment (n = 42). There were significant benefits of early treatment for times to rate (155.9 ± 299.8 vs 407.6 ± 376.9 minutes, (P < .001) and rhythm control (400.4 ± 845 vs 1038.5 ± 1158.4 minutes, P < .001), reduction in dose needed for rate control (28.2 ± 45.2 vs 66.5 ± 137.5 mg, P < .025), and significant reduction in pediatric cardiac intensive care unit stay (3.32 ± 1.9 vs 5.26 ± 4.27 days, P < .01). There were continuous improvements in heart rate, blood pressure, and filling pressures without additional inotropic requirements or side effects.ConclusionEarly treatment of postoperative tachyarrhythmia with amiodarone according to a standardized treatment protocol is safe and has beneficial effects on arrhythmia control and pediatric cardiac intensive care unit stay. Effects of timing of inception of amiodarone antiarrhythmic treatment after corrective surgery for congenital heart defects are not yet well defined. In a 10-year prospective observational study, 71 of 2651 patients (2885 procedures, 2106 bypass procedures) received amiodarone for newly detected postoperative atrial (n = 70) or ventricular (n = 7) tachyarrhythmia: early treatment (initiation within 60 minutes of arrhythmia detection) and late treatment (after that). From an interim analysis, a treatment protocol was established (32 patients). Inotropic requirements were monitored, as were heart rate, blood pressure, central venous pressure, and sedation requirements. With early treatment (n = 29), delay before start of amiodarone was 40.7 ± 21.9 minutes, versus 227.7 ± 228.1 minutes (P < .001) with late treatment (n = 42). There were significant benefits of early treatment for times to rate (155.9 ± 299.8 vs 407.6 ± 376.9 minutes, (P < .001) and rhythm control (400.4 ± 845 vs 1038.5 ± 1158.4 minutes, P < .001), reduction in dose needed for rate control (28.2 ± 45.2 vs 66.5 ± 137.5 mg, P < .025), and significant reduction in pediatric cardiac intensive care unit stay (3.32 ± 1.9 vs 5.26 ± 4.27 days, P < .01). There were continuous improvements in heart rate, blood pressure, and filling pressures without additional inotropic requirements or side effects. Early treatment of postoperative tachyarrhythmia with amiodarone according to a standardized treatment protocol is safe and has beneficial effects on arrhythmia control and pediatric cardiac intensive care unit stay." @default.
• W2093000550 created "2016-06-24" @default.
• W2093000550 creator A5043130465 @default.
• W2093000550 creator A5049398712 @default.
• W2093000550 date "2008-11-01" @default.
• W2093000550 modified "2023-09-26" @default.
• W2093000550 title "Impact of early and standardized treatment with amiodarone on therapeutic success and outcome in pediatric patients with postoperative tachyarrhythmia" @default.
• W2093000550 cites W1542706635 @default.
• W2093000550 cites W1972578773 @default.
• W2093000550 cites W1974789187 @default.
• W2093000550 cites W1975740742 @default.
• W2093000550 cites W1984676293 @default.
• W2093000550 cites W1992582857 @default.
• W2093000550 cites W1996670408 @default.
• W2093000550 cites W2003321268 @default.
• W2093000550 cites W2007678836 @default.
• W2093000550 cites W2014887130 @default.
• W2093000550 cites W2024635436 @default.
• W2093000550 cites W2028067467 @default.
• W2093000550 cites W2040647685 @default.
• W2093000550 cites W2041830092 @default.
• W2093000550 cites W2045031346 @default.
• W2093000550 cites W2045682371 @default.
• W2093000550 cites W2048002060 @default.
• W2093000550 cites W2053653089 @default.
• W2093000550 cites W2067497418 @default.
• W2093000550 cites W2070598889 @default.
• W2093000550 cites W2072840939 @default.
• W2093000550 cites W2079296381 @default.
• W2093000550 cites W2089310426 @default.
• W2093000550 cites W2089929230 @default.
• W2093000550 cites W2116241814 @default.
• W2093000550 cites W2132059115 @default.
• W2093000550 cites W2138373808 @default.
• W2093000550 cites W2141513595 @default.
• W2093000550 cites W2141900287 @default.
• W2093000550 cites W2145446765 @default.
• W2093000550 cites W2159303521 @default.
• W2093000550 cites W2159321277 @default.
• W2093000550 cites W2168348445 @default.
• W2093000550 cites W2171462210 @default.
• W2093000550 cites W2411012994 @default.
• W2093000550 doi "https://doi.org/10.1016/j.jtcvs.2008.04.011" @default.
• W2093000550 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19026806" @default.
• W2093000550 hasPublicationYear "2008" @default.
• W2093000550 type Work @default.
• W2093000550 sameAs 2093000550 @default.
• W2093000550 citedByCount "40" @default.
• W2093000550 countsByYear W20930005502012 @default.
• W2093000550 countsByYear W20930005502014 @default.
• W2093000550 countsByYear W20930005502015 @default.
• W2093000550 countsByYear W20930005502016 @default.
• W2093000550 countsByYear W20930005502017 @default.
• W2093000550 countsByYear W20930005502018 @default.
• W2093000550 countsByYear W20930005502019 @default.
• W2093000550 countsByYear W20930005502020 @default.
• W2093000550 countsByYear W20930005502021 @default.
• W2093000550 countsByYear W20930005502022 @default.
• W2093000550 countsByYear W20930005502023 @default.
• W2093000550 crossrefType "journal-article" @default.
• W2093000550 hasAuthorship W2093000550A5043130465 @default.
• W2093000550 hasAuthorship W2093000550A5049398712 @default.
• W2093000550 hasBestOaLocation W20930005501 @default.
• W2093000550 hasConcept C126322002 @default.
• W2093000550 hasConcept C164705383 @default.
• W2093000550 hasConcept C177713679 @default.
• W2093000550 hasConcept C2776376669 @default.
• W2093000550 hasConcept C2776814716 @default.
• W2093000550 hasConcept C2777953023 @default.
• W2093000550 hasConcept C2778094803 @default.
• W2093000550 hasConcept C2778939556 @default.
• W2093000550 hasConcept C2779161974 @default.
• W2093000550 hasConcept C42219234 @default.
• W2093000550 hasConcept C71924100 @default.
• W2093000550 hasConcept C84393581 @default.
• W2093000550 hasConceptScore W2093000550C126322002 @default.
• W2093000550 hasConceptScore W2093000550C164705383 @default.
• W2093000550 hasConceptScore W2093000550C177713679 @default.
• W2093000550 hasConceptScore W2093000550C2776376669 @default.
• W2093000550 hasConceptScore W2093000550C2776814716 @default.
• W2093000550 hasConceptScore W2093000550C2777953023 @default.
• W2093000550 hasConceptScore W2093000550C2778094803 @default.
• W2093000550 hasConceptScore W2093000550C2778939556 @default.
• W2093000550 hasConceptScore W2093000550C2779161974 @default.
• W2093000550 hasConceptScore W2093000550C42219234 @default.
• W2093000550 hasConceptScore W2093000550C71924100 @default.
• W2093000550 hasConceptScore W2093000550C84393581 @default.
• W2093000550 hasIssue "5" @default.
• W2093000550 hasLocation W20930005501 @default.
• W2093000550 hasLocation W20930005502 @default.
• W2093000550 hasOpenAccess W2093000550 @default.
• W2093000550 hasPrimaryLocation W20930005501 @default.
• W2093000550 hasRelatedWork W1794600573 @default.
• W2093000550 hasRelatedWork W1988265689 @default.
• W2093000550 hasRelatedWork W2091940969 @default.
• W2093000550 hasRelatedWork W2151610778 @default.
• W2093000550 hasRelatedWork W2348523392 @default.
• W2093000550 hasRelatedWork W2359780091 @default.

• next