Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093012009> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2093012009 endingPage "103" @default.
- W2093012009 startingPage "95" @default.
- W2093012009 abstract "Specific factors that determine the cell fate in early embryogenesis are modulated during interaction of signaling pathways to form a unique regulatory network inside the cell, which is essential for differentiation of various cell populations. We carried out a comparative study of expression of the genes of TGFβ growth factors and their receptors at the initial stages of differentiation of the embryonic stem cells, during formation of spheroids of the embryonic teratocarcinoma cells, and during growth of neoplastic cells in vivo in immunodeficient mice. The patterns of expression of the genes Activin, Nodal, Lefty1, Lefty2, BMP, and TGFβ1 and their receptors ActRI, ActRII, BMPRI, TGFβ1R1, and Tdgf proved to be identical. Expression of α-fetoprotein and transcription factor Gata4 protein, specific for the primary endoderm, was detected in the embryonic teratocarcinoma cells. In Undifferentiated embryonic stem cells, expression of Gata4 was found at the mRNA level, while expression at the level of proteins appeared only in the primary endoderm cells in the embryoid bodies. The results obtained suggest that despite the existence of similar signaling systems in the embryonic stem and teratocarcinoma cells, the presence of different intracellular specific factors forms radically different regulatory pathways, which determine the program of their differentiation." @default.
- W2093012009 created "2016-06-24" @default.
- W2093012009 creator A5034444761 @default.
- W2093012009 creator A5066520133 @default.
- W2093012009 date "2007-03-01" @default.
- W2093012009 modified "2023-09-26" @default.
- W2093012009 title "Comparative analysis of expression of TGFβ family factors and their receptors in mouse embryonic stem and teratocarcinoma cells" @default.
- W2093012009 cites W1867279571 @default.
- W2093012009 cites W1898918895 @default.
- W2093012009 cites W1966697925 @default.
- W2093012009 cites W1970200029 @default.
- W2093012009 cites W1976354992 @default.
- W2093012009 cites W1979313973 @default.
- W2093012009 cites W1994758141 @default.
- W2093012009 cites W2006499356 @default.
- W2093012009 cites W2036552662 @default.
- W2093012009 cites W2045899482 @default.
- W2093012009 cites W2047087429 @default.
- W2093012009 cites W2057159461 @default.
- W2093012009 cites W2066090522 @default.
- W2093012009 cites W2074742645 @default.
- W2093012009 cites W2074858377 @default.
- W2093012009 cites W2079625772 @default.
- W2093012009 cites W2089426706 @default.
- W2093012009 cites W2096736856 @default.
- W2093012009 cites W2102085111 @default.
- W2093012009 cites W2106115330 @default.
- W2093012009 cites W2110301828 @default.
- W2093012009 cites W2110555613 @default.
- W2093012009 cites W2126851387 @default.
- W2093012009 cites W2132729210 @default.
- W2093012009 cites W2148440651 @default.
- W2093012009 cites W2154568166 @default.
- W2093012009 cites W2161949020 @default.
- W2093012009 cites W2164563970 @default.
- W2093012009 cites W224011504 @default.
- W2093012009 doi "https://doi.org/10.1134/s1062360407020063" @default.
- W2093012009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17479535" @default.
- W2093012009 hasPublicationYear "2007" @default.
- W2093012009 type Work @default.
- W2093012009 sameAs 2093012009 @default.
- W2093012009 citedByCount "2" @default.
- W2093012009 countsByYear W20930120092014 @default.
- W2093012009 countsByYear W20930120092017 @default.
- W2093012009 crossrefType "journal-article" @default.
- W2093012009 hasAuthorship W2093012009A5034444761 @default.
- W2093012009 hasAuthorship W2093012009A5066520133 @default.
- W2093012009 hasConcept C104317684 @default.
- W2093012009 hasConcept C143948831 @default.
- W2093012009 hasConcept C145103041 @default.
- W2093012009 hasConcept C148738053 @default.
- W2093012009 hasConcept C153911025 @default.
- W2093012009 hasConcept C20875687 @default.
- W2093012009 hasConcept C26805974 @default.
- W2093012009 hasConcept C2777164004 @default.
- W2093012009 hasConcept C28328180 @default.
- W2093012009 hasConcept C2908788973 @default.
- W2093012009 hasConcept C54355233 @default.
- W2093012009 hasConcept C86803240 @default.
- W2093012009 hasConcept C95444343 @default.
- W2093012009 hasConceptScore W2093012009C104317684 @default.
- W2093012009 hasConceptScore W2093012009C143948831 @default.
- W2093012009 hasConceptScore W2093012009C145103041 @default.
- W2093012009 hasConceptScore W2093012009C148738053 @default.
- W2093012009 hasConceptScore W2093012009C153911025 @default.
- W2093012009 hasConceptScore W2093012009C20875687 @default.
- W2093012009 hasConceptScore W2093012009C26805974 @default.
- W2093012009 hasConceptScore W2093012009C2777164004 @default.
- W2093012009 hasConceptScore W2093012009C28328180 @default.
- W2093012009 hasConceptScore W2093012009C2908788973 @default.
- W2093012009 hasConceptScore W2093012009C54355233 @default.
- W2093012009 hasConceptScore W2093012009C86803240 @default.
- W2093012009 hasConceptScore W2093012009C95444343 @default.
- W2093012009 hasIssue "2" @default.
- W2093012009 hasLocation W20930120091 @default.
- W2093012009 hasLocation W20930120092 @default.
- W2093012009 hasOpenAccess W2093012009 @default.
- W2093012009 hasPrimaryLocation W20930120091 @default.
- W2093012009 hasRelatedWork W1603508604 @default.
- W2093012009 hasRelatedWork W1972679169 @default.
- W2093012009 hasRelatedWork W1975572622 @default.
- W2093012009 hasRelatedWork W2022682551 @default.
- W2093012009 hasRelatedWork W2066018966 @default.
- W2093012009 hasRelatedWork W2093012009 @default.
- W2093012009 hasRelatedWork W2133295711 @default.
- W2093012009 hasRelatedWork W2281526892 @default.
- W2093012009 hasRelatedWork W2418080569 @default.
- W2093012009 hasRelatedWork W4210553678 @default.
- W2093012009 hasVolume "38" @default.
- W2093012009 isParatext "false" @default.
- W2093012009 isRetracted "false" @default.
- W2093012009 magId "2093012009" @default.
- W2093012009 workType "article" @default.