Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093036934> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2093036934 endingPage "464" @default.
- W2093036934 startingPage "459" @default.
- W2093036934 abstract "Over a three-year period, more than 500 psychiatric patients of various diagnostic categories were treated with imipramine hydrochloride. It was demonstrated that the compound has potent antidepressant action. Best responses were obtained in cases of endogenous depression showing the typical symptoms of mental and motor retardation, fatigue, feeling of heaviness, hopelessness, guilt, and despair. The condition is furthermore characterized by the aggravation of symptoms in the morning with a tendency to improvement during the day. Treatment with imipramine hydrochloride resulted in full or social recovery in a high percentage of the patients. As a rule, the initial response was evident within 2 to 3 days, while in some cases 1 to 4 weeks of therapy were required. In view of the symptomatic nature of the action of imipramine hydrochloride, therapy must be maintained as long as the illness lasts. The side effects noted were relatively slight, and with the exception of one case of severe allergic exanthema necessitating discontinuance of treatment, no serious complications were encountered. In some cases of depression, particularly those associated with organic brain damage or schizophrenic psychosis, transitory states of agitation or exacerbation of the psychotic features were noted. These observations suggest the importance of a proper selection of the patients as to type and etiology of depression. While in a number of instances, neurotic, schizophrenic or other depressions were also benefited by the drug, particularly when used in combination with chlorpromazine, electroshock or psychotherapy, it is concluded that imipramine hydrochloride is primarily indicated and effective in the treatment of endogenous depression." @default.
- W2093036934 created "2016-06-24" @default.
- W2093036934 creator A5011759281 @default.
- W2093036934 date "1958-11-01" @default.
- W2093036934 modified "2023-10-03" @default.
- W2093036934 title "THE TREATMENT OF DEPRESSIVE STATES WITH G 22355 (IMIPRAMINE HYDROCHLORIDE)" @default.
- W2093036934 doi "https://doi.org/10.1176/ajp.115.5.459" @default.
- W2093036934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13583250" @default.
- W2093036934 hasPublicationYear "1958" @default.
- W2093036934 type Work @default.
- W2093036934 sameAs 2093036934 @default.
- W2093036934 citedByCount "480" @default.
- W2093036934 countsByYear W20930369342012 @default.
- W2093036934 countsByYear W20930369342013 @default.
- W2093036934 countsByYear W20930369342014 @default.
- W2093036934 countsByYear W20930369342015 @default.
- W2093036934 countsByYear W20930369342016 @default.
- W2093036934 countsByYear W20930369342017 @default.
- W2093036934 countsByYear W20930369342018 @default.
- W2093036934 countsByYear W20930369342019 @default.
- W2093036934 countsByYear W20930369342020 @default.
- W2093036934 countsByYear W20930369342021 @default.
- W2093036934 countsByYear W20930369342022 @default.
- W2093036934 countsByYear W20930369342023 @default.
- W2093036934 crossrefType "journal-article" @default.
- W2093036934 hasAuthorship W2093036934A5011759281 @default.
- W2093036934 hasConcept C118552586 @default.
- W2093036934 hasConcept C126322002 @default.
- W2093036934 hasConcept C137627325 @default.
- W2093036934 hasConcept C139719470 @default.
- W2093036934 hasConcept C142724271 @default.
- W2093036934 hasConcept C15744967 @default.
- W2093036934 hasConcept C162324750 @default.
- W2093036934 hasConcept C204787440 @default.
- W2093036934 hasConcept C2776412080 @default.
- W2093036934 hasConcept C2776867660 @default.
- W2093036934 hasConcept C2777014857 @default.
- W2093036934 hasConcept C2777330709 @default.
- W2093036934 hasConcept C2779145073 @default.
- W2093036934 hasConcept C2779177272 @default.
- W2093036934 hasConcept C2779727114 @default.
- W2093036934 hasConcept C2780163958 @default.
- W2093036934 hasConcept C558461103 @default.
- W2093036934 hasConcept C71924100 @default.
- W2093036934 hasConceptScore W2093036934C118552586 @default.
- W2093036934 hasConceptScore W2093036934C126322002 @default.
- W2093036934 hasConceptScore W2093036934C137627325 @default.
- W2093036934 hasConceptScore W2093036934C139719470 @default.
- W2093036934 hasConceptScore W2093036934C142724271 @default.
- W2093036934 hasConceptScore W2093036934C15744967 @default.
- W2093036934 hasConceptScore W2093036934C162324750 @default.
- W2093036934 hasConceptScore W2093036934C204787440 @default.
- W2093036934 hasConceptScore W2093036934C2776412080 @default.
- W2093036934 hasConceptScore W2093036934C2776867660 @default.
- W2093036934 hasConceptScore W2093036934C2777014857 @default.
- W2093036934 hasConceptScore W2093036934C2777330709 @default.
- W2093036934 hasConceptScore W2093036934C2779145073 @default.
- W2093036934 hasConceptScore W2093036934C2779177272 @default.
- W2093036934 hasConceptScore W2093036934C2779727114 @default.
- W2093036934 hasConceptScore W2093036934C2780163958 @default.
- W2093036934 hasConceptScore W2093036934C558461103 @default.
- W2093036934 hasConceptScore W2093036934C71924100 @default.
- W2093036934 hasIssue "5" @default.
- W2093036934 hasLocation W20930369341 @default.
- W2093036934 hasLocation W20930369342 @default.
- W2093036934 hasOpenAccess W2093036934 @default.
- W2093036934 hasPrimaryLocation W20930369341 @default.
- W2093036934 hasRelatedWork W137284767 @default.
- W2093036934 hasRelatedWork W2040403375 @default.
- W2093036934 hasRelatedWork W2042600514 @default.
- W2093036934 hasRelatedWork W2046629821 @default.
- W2093036934 hasRelatedWork W2405139333 @default.
- W2093036934 hasRelatedWork W2411884052 @default.
- W2093036934 hasRelatedWork W2417825661 @default.
- W2093036934 hasRelatedWork W3137166182 @default.
- W2093036934 hasRelatedWork W3202003670 @default.
- W2093036934 hasRelatedWork W4286969835 @default.
- W2093036934 hasVolume "115" @default.
- W2093036934 isParatext "false" @default.
- W2093036934 isRetracted "false" @default.
- W2093036934 magId "2093036934" @default.
- W2093036934 workType "article" @default.