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- W2093095529 abstract "RNA binding proteins (RBPs) and RNA interaction is an emerging topic in molecular biology. Many reports showed that such interactions contribute to many cellular processes as well as disease development. Several standard in vitro and in vivo methods were developed to fulfill the needs of this RBP–RNA interaction study to explore their biological functions. However, these methods have their limitations in terms of throughput. In this review, we emphasize two important high throughput methods to studying RBP–RNA interactions, affinity purification and protein microarray. These methods have recently become robust techniques regarding their efficiency in systematically analyzing RBP–RNA interactions. Here, we provide technique overviews, strategies and applications of these methods during biological research. Although these technologies are just beginning to be explored, they will be most important methods in this study." @default.
- W2093095529 created "2016-06-24" @default.
- W2093095529 creator A5009531702 @default.
- W2093095529 creator A5061083858 @default.
- W2093095529 creator A5091799367 @default.
- W2093095529 date "2014-07-15" @default.
- W2093095529 modified "2023-09-30" @default.
- W2093095529 title "High throughput platform to explore RNA–protein interactomes" @default.
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- W2093095529 doi "https://doi.org/10.3109/07388551.2014.922916" @default.
- W2093095529 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25025276" @default.
- W2093095529 hasPublicationYear "2014" @default.
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