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- W2093118575 abstract "Determinations of high-energy phosphates (PC and ATP) were carried out in rabbit hearts (perfused at 23 °C with a 2.1 hyperkalemic solution of DMSO for different periods of time), some of which underwent an additional washingout procedure and were reperfused. This procedure always caused modifications in the ATP and PC concentrations compatible with a good viability of the heart. The time of contact rather than concentration seems to be responsible for deterioration as long as DMSO concentration does not exceed 2.1 m/liter. Assays of enzymes (CPK, LDH) performed throughout the same procedure showed that the figures obtained were compatible with a brief but temporary modification of membrane permeability such as those induced by a hyperkalemic perfusion, but that the part played by DMSO in these modifications appears to be only slight in the majority of cases." @default.
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- W2093118575 date "1972-12-01" @default.
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- W2093118575 title "Evaluation of dimethylsulfoxide (DMSO) injury to the myocardial cell by determination of high-energy phosphate reserve and enzyme release" @default.
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- W2093118575 doi "https://doi.org/10.1016/0011-2240(72)90168-x" @default.
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