FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093173664> ?p ?o ?g. }

• W2093173664 endingPage "310" @default.
• W2093173664 startingPage "300" @default.
• W2093173664 abstract "Glutamine synthetase (EC 6.3.1.2) was localized within the matrix compartment of avian liver mitochondria. The submitochondrial localization of this enzyme was determined by the digitonin-Lubrol method of Schnaitman and Greenawalt (35). The matrix fraction contained over 74% of the glutamine synthetase activity and the major proportion of the matirx marker enzymes, malate dehydrogenase (71%), NADP-dependent isocitrate dehydrogenase (83%), and glutamate dehydrogenase (57%). The highest specific activities of these enzymes were also found in the matrix compartment. Oxidation of glutamine by avian liver mitochondria was substantially less than that of glutamate. Bromofuroate, an inhibitor of glutamate dehydrogenase, blocked oxidation of glutamate and of glutamine whereas aminoxyacetate, a transaminase inhibitor, had little or no effect with either substrate. These results indicate that glutamine metabolism is probably initiated by the conversion of glutamine to glutamate rather than to an alpha-keto acid. The localization of a glutaminase activity within avian liver mitochondria plus the absence of an active mitochondrial glutamine transaminase is consistent with the differential effects of the transaminase and glutamate dehydrogenase inhibitors. The high glutamine synthetase activity (40:1) suggests that mitochondrial catabolism of glutamine is minimal, freeing most of the glutamine synthesized for purine (uric acid) biosynthesis." @default.
• W2093173664 created "2016-06-24" @default.
• W2093173664 creator A5018239728 @default.
• W2093173664 creator A5018864792 @default.
• W2093173664 date "1977-05-01" @default.
• W2093173664 modified "2023-09-28" @default.
• W2093173664 title "Submitochondrial localization and function of enzymes of glutamine metabolism in avian liver." @default.
• W2093173664 cites W144601562 @default.
• W2093173664 cites W1484603920 @default.
• W2093173664 cites W1494587255 @default.
• W2093173664 cites W1509752586 @default.
• W2093173664 cites W1529085729 @default.
• W2093173664 cites W1535442687 @default.
• W2093173664 cites W1553837257 @default.
• W2093173664 cites W1569351449 @default.
• W2093173664 cites W1580146889 @default.
• W2093173664 cites W1595324604 @default.
• W2093173664 cites W1655763873 @default.
• W2093173664 cites W166608938 @default.
• W2093173664 cites W1775749144 @default.
• W2093173664 cites W182121841 @default.
• W2093173664 cites W1875092895 @default.
• W2093173664 cites W1965862508 @default.
• W2093173664 cites W1969805452 @default.
• W2093173664 cites W1977880602 @default.
• W2093173664 cites W1983357897 @default.
• W2093173664 cites W1984633970 @default.
• W2093173664 cites W1989590880 @default.
• W2093173664 cites W2045209911 @default.
• W2093173664 cites W2046560945 @default.
• W2093173664 cites W2125562918 @default.
• W2093173664 cites W2200460224 @default.
• W2093173664 cites W2341890941 @default.
• W2093173664 cites W72041974 @default.
• W2093173664 cites W2440788774 @default.
• W2093173664 doi "https://doi.org/10.1083/jcb.73.2.300" @default.
• W2093173664 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2109915" @default.
• W2093173664 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16018" @default.
• W2093173664 hasPublicationYear "1977" @default.
• W2093173664 type Work @default.
• W2093173664 sameAs 2093173664 @default.
• W2093173664 citedByCount "27" @default.
• W2093173664 countsByYear W20931736642013 @default.
• W2093173664 countsByYear W20931736642021 @default.
• W2093173664 crossrefType "journal-article" @default.
• W2093173664 hasAuthorship W2093173664A5018239728 @default.
• W2093173664 hasAuthorship W2093173664A5018864792 @default.
• W2093173664 hasBestOaLocation W20931736641 @default.
• W2093173664 hasConcept C109549099 @default.
• W2093173664 hasConcept C11701378 @default.
• W2093173664 hasConcept C132901563 @default.
• W2093173664 hasConcept C170493617 @default.
• W2093173664 hasConcept C181199279 @default.
• W2093173664 hasConcept C191771488 @default.
• W2093173664 hasConcept C2776317432 @default.
• W2093173664 hasConcept C2776877979 @default.
• W2093173664 hasConcept C2777150147 @default.
• W2093173664 hasConcept C2777202666 @default.
• W2093173664 hasConcept C2779289688 @default.
• W2093173664 hasConcept C2779349466 @default.
• W2093173664 hasConcept C515207424 @default.
• W2093173664 hasConcept C55493867 @default.
• W2093173664 hasConcept C60538801 @default.
• W2093173664 hasConcept C61174792 @default.
• W2093173664 hasConcept C86803240 @default.
• W2093173664 hasConcept C98539663 @default.
• W2093173664 hasConceptScore W2093173664C109549099 @default.
• W2093173664 hasConceptScore W2093173664C11701378 @default.
• W2093173664 hasConceptScore W2093173664C132901563 @default.
• W2093173664 hasConceptScore W2093173664C170493617 @default.
• W2093173664 hasConceptScore W2093173664C181199279 @default.
• W2093173664 hasConceptScore W2093173664C191771488 @default.
• W2093173664 hasConceptScore W2093173664C2776317432 @default.
• W2093173664 hasConceptScore W2093173664C2776877979 @default.
• W2093173664 hasConceptScore W2093173664C2777150147 @default.
• W2093173664 hasConceptScore W2093173664C2777202666 @default.
• W2093173664 hasConceptScore W2093173664C2779289688 @default.
• W2093173664 hasConceptScore W2093173664C2779349466 @default.
• W2093173664 hasConceptScore W2093173664C515207424 @default.
• W2093173664 hasConceptScore W2093173664C55493867 @default.
• W2093173664 hasConceptScore W2093173664C60538801 @default.
• W2093173664 hasConceptScore W2093173664C61174792 @default.
• W2093173664 hasConceptScore W2093173664C86803240 @default.
• W2093173664 hasConceptScore W2093173664C98539663 @default.
• W2093173664 hasIssue "2" @default.
• W2093173664 hasLocation W20931736641 @default.
• W2093173664 hasLocation W20931736642 @default.
• W2093173664 hasLocation W20931736643 @default.
• W2093173664 hasLocation W20931736644 @default.
• W2093173664 hasOpenAccess W2093173664 @default.
• W2093173664 hasPrimaryLocation W20931736641 @default.
• W2093173664 hasRelatedWork W1712989564 @default.
• W2093173664 hasRelatedWork W1820387122 @default.
• W2093173664 hasRelatedWork W1864249421 @default.
• W2093173664 hasRelatedWork W1980057149 @default.
• W2093173664 hasRelatedWork W1988929832 @default.
• W2093173664 hasRelatedWork W2065524010 @default.
• W2093173664 hasRelatedWork W2093173664 @default.

• next