Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093182862> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2093182862 endingPage "601" @default.
- W2093182862 startingPage "597" @default.
- W2093182862 abstract "Pudendal nerve stimulation is known to have a potential modulative effect on bladder function. However, even if its efficiency has been established for various neurogenic and non-neurogenic bladder dysfunctions, the underlying neuronal mechanism, and the involved pathways in humans remain unknown. In this prospective study we focused on the effects of pudendal nerve stimulation in complete spinal cord injured patients to identify neuromodulative processes that occur on spinal level.Twenty complete spinal male presenting with upper motor neuron lesion and neurogenic incontinence underwent pudendal nerve stimulation. Bladder, bladder neck (BN), and external urethral sphincter (EUS) pressures were continuously recorded with a three channel microtip pressure transducer catheter. Fifty six pudendal stimulations using biphasic rectangular impulses (0.2 ms, 10 Hz) with intensities up to 100 mA were applied to the dorsal penile nerve. In six patients, 18 stimulations were repeated after intravenous (i.v.) administration of 7 mg phentolamine.Mean BN and EUS pressure increased during stimulation significantly (P < 0.001). The latencies to the EUS responses range between 27 and 41 ms and those to the BN responses between 188 and 412 ms. Phentolamine decreased initial BN pressure and reduced the pressure rise during stimulation significantly (P < 0.05).Pudendal nerve stimulation evoked somatic responses in the EUS and autonomic responses in the smooth muscle sphincter controlling the BN. Longer latencies of the BN responses and the sensitivity to the alpha-blocking agent phentolamine suggest that sympathetic alpha-adrenergic fibers are involved. Somatic afferent fibers of the pudendal nerve are supposed to project on sympathetic thoracolumbar neurons to the BN and modulate their function. This neuromodulative effect works exclusively at the spinal level and appears to be at least partly responsible for BN competence and at least continence." @default.
- W2093182862 created "2016-06-24" @default.
- W2093182862 creator A5041662346 @default.
- W2093182862 creator A5044302538 @default.
- W2093182862 creator A5055617419 @default.
- W2093182862 creator A5069598374 @default.
- W2093182862 creator A5069955470 @default.
- W2093182862 date "2003-01-01" @default.
- W2093182862 modified "2023-10-18" @default.
- W2093182862 title "Afferent fibers of the pudendal nerve modulate sympathetic neurons controlling the bladder neck" @default.
- W2093182862 cites W1489140565 @default.
- W2093182862 cites W1566870511 @default.
- W2093182862 cites W180900315 @default.
- W2093182862 cites W1969279276 @default.
- W2093182862 cites W1983304221 @default.
- W2093182862 cites W2028379341 @default.
- W2093182862 cites W2030384764 @default.
- W2093182862 cites W2054403476 @default.
- W2093182862 cites W2056583262 @default.
- W2093182862 cites W2081003753 @default.
- W2093182862 cites W2125390509 @default.
- W2093182862 cites W2144046278 @default.
- W2093182862 cites W2167542451 @default.
- W2093182862 cites W2402181113 @default.
- W2093182862 cites W2414805474 @default.
- W2093182862 cites W2415246301 @default.
- W2093182862 cites W2464258360 @default.
- W2093182862 cites W86705196 @default.
- W2093182862 doi "https://doi.org/10.1002/nau.10134" @default.
- W2093182862 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12951671" @default.
- W2093182862 hasPublicationYear "2003" @default.
- W2093182862 type Work @default.
- W2093182862 sameAs 2093182862 @default.
- W2093182862 citedByCount "57" @default.
- W2093182862 countsByYear W20931828622012 @default.
- W2093182862 countsByYear W20931828622013 @default.
- W2093182862 countsByYear W20931828622014 @default.
- W2093182862 countsByYear W20931828622015 @default.
- W2093182862 countsByYear W20931828622016 @default.
- W2093182862 countsByYear W20931828622017 @default.
- W2093182862 countsByYear W20931828622018 @default.
- W2093182862 countsByYear W20931828622019 @default.
- W2093182862 countsByYear W20931828622020 @default.
- W2093182862 countsByYear W20931828622021 @default.
- W2093182862 countsByYear W20931828622022 @default.
- W2093182862 countsByYear W20931828622023 @default.
- W2093182862 crossrefType "journal-article" @default.
- W2093182862 hasAuthorship W2093182862A5041662346 @default.
- W2093182862 hasAuthorship W2093182862A5044302538 @default.
- W2093182862 hasAuthorship W2093182862A5055617419 @default.
- W2093182862 hasAuthorship W2093182862A5069598374 @default.
- W2093182862 hasAuthorship W2093182862A5069955470 @default.
- W2093182862 hasConcept C118552586 @default.
- W2093182862 hasConcept C126322002 @default.
- W2093182862 hasConcept C126894567 @default.
- W2093182862 hasConcept C24998067 @default.
- W2093182862 hasConcept C2777085111 @default.
- W2093182862 hasConcept C2779013793 @default.
- W2093182862 hasConcept C2780253649 @default.
- W2093182862 hasConcept C2780682423 @default.
- W2093182862 hasConcept C2780775167 @default.
- W2093182862 hasConcept C42219234 @default.
- W2093182862 hasConcept C71924100 @default.
- W2093182862 hasConcept C88537330 @default.
- W2093182862 hasConceptScore W2093182862C118552586 @default.
- W2093182862 hasConceptScore W2093182862C126322002 @default.
- W2093182862 hasConceptScore W2093182862C126894567 @default.
- W2093182862 hasConceptScore W2093182862C24998067 @default.
- W2093182862 hasConceptScore W2093182862C2777085111 @default.
- W2093182862 hasConceptScore W2093182862C2779013793 @default.
- W2093182862 hasConceptScore W2093182862C2780253649 @default.
- W2093182862 hasConceptScore W2093182862C2780682423 @default.
- W2093182862 hasConceptScore W2093182862C2780775167 @default.
- W2093182862 hasConceptScore W2093182862C42219234 @default.
- W2093182862 hasConceptScore W2093182862C71924100 @default.
- W2093182862 hasConceptScore W2093182862C88537330 @default.
- W2093182862 hasIssue "6" @default.
- W2093182862 hasLocation W20931828621 @default.
- W2093182862 hasLocation W20931828622 @default.
- W2093182862 hasOpenAccess W2093182862 @default.
- W2093182862 hasPrimaryLocation W20931828621 @default.
- W2093182862 hasRelatedWork W1504978234 @default.
- W2093182862 hasRelatedWork W1965327003 @default.
- W2093182862 hasRelatedWork W2022857271 @default.
- W2093182862 hasRelatedWork W2048875529 @default.
- W2093182862 hasRelatedWork W2060699123 @default.
- W2093182862 hasRelatedWork W2079701232 @default.
- W2093182862 hasRelatedWork W2093182862 @default.
- W2093182862 hasRelatedWork W2298671972 @default.
- W2093182862 hasRelatedWork W2316055721 @default.
- W2093182862 hasRelatedWork W2425680246 @default.
- W2093182862 hasVolume "22" @default.
- W2093182862 isParatext "false" @default.
- W2093182862 isRetracted "false" @default.
- W2093182862 magId "2093182862" @default.
- W2093182862 workType "article" @default.