FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093200633> ?p ?o ?g. }

• W2093200633 endingPage "497" @default.
• W2093200633 startingPage "494" @default.
• W2093200633 abstract "A new class of 2-oxo-tetrahydro-1,8-naphthyridine-based protein farnesyltransferase inhibitors were synthesized and found to inhibit protein farnesyltransferase from the malaria parasite with potencies in the low nanomolar range. The compounds were much less potent on mammalian protein prenyltransferases. Two of the compounds block the growth of malaria in culture with potencies in the sub-micromolar range. Some of the compounds were found to be much more metabolically stable than previously described tetrahydroquinoline-based protein farnesyltransferase inhibitors." @default.
• W2093200633 created "2016-06-24" @default.
• W2093200633 creator A5005944101 @default.
• W2093200633 creator A5010879006 @default.
• W2093200633 creator A5026524686 @default.
• W2093200633 creator A5050852618 @default.
• W2093200633 creator A5054562365 @default.
• W2093200633 creator A5054616118 @default.
• W2093200633 creator A5065096568 @default.
• W2093200633 creator A5080485549 @default.
• W2093200633 date "2008-01-01" @default.
• W2093200633 modified "2023-10-16" @default.
• W2093200633 title "2-Oxo-tetrahydro-1,8-naphthyridines as selective inhibitors of malarial protein farnesyltransferase and as anti-malarials" @default.
• W2093200633 cites W2022454349 @default.
• W2093200633 cites W2070854001 @default.
• W2093200633 cites W2076535269 @default.
• W2093200633 cites W2116864669 @default.
• W2093200633 cites W2118158662 @default.
• W2093200633 cites W2126638912 @default.
• W2093200633 cites W2171846730 @default.
• W2093200633 doi "https://doi.org/10.1016/j.bmcl.2007.11.104" @default.
• W2093200633 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2275803" @default.
• W2093200633 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18077162" @default.
• W2093200633 hasPublicationYear "2008" @default.
• W2093200633 type Work @default.
• W2093200633 sameAs 2093200633 @default.
• W2093200633 citedByCount "47" @default.
• W2093200633 countsByYear W20932006332012 @default.
• W2093200633 countsByYear W20932006332013 @default.
• W2093200633 countsByYear W20932006332014 @default.
• W2093200633 countsByYear W20932006332015 @default.
• W2093200633 countsByYear W20932006332016 @default.
• W2093200633 countsByYear W20932006332017 @default.
• W2093200633 countsByYear W20932006332018 @default.
• W2093200633 countsByYear W20932006332019 @default.
• W2093200633 countsByYear W20932006332020 @default.
• W2093200633 countsByYear W20932006332021 @default.
• W2093200633 countsByYear W20932006332022 @default.
• W2093200633 countsByYear W20932006332023 @default.
• W2093200633 crossrefType "journal-article" @default.
• W2093200633 hasAuthorship W2093200633A5005944101 @default.
• W2093200633 hasAuthorship W2093200633A5010879006 @default.
• W2093200633 hasAuthorship W2093200633A5026524686 @default.
• W2093200633 hasAuthorship W2093200633A5050852618 @default.
• W2093200633 hasAuthorship W2093200633A5054562365 @default.
• W2093200633 hasAuthorship W2093200633A5054616118 @default.
• W2093200633 hasAuthorship W2093200633A5065096568 @default.
• W2093200633 hasAuthorship W2093200633A5080485549 @default.
• W2093200633 hasBestOaLocation W20932006332 @default.
• W2093200633 hasConcept C181199279 @default.
• W2093200633 hasConcept C185592680 @default.
• W2093200633 hasConcept C202751555 @default.
• W2093200633 hasConcept C203014093 @default.
• W2093200633 hasConcept C2777827897 @default.
• W2093200633 hasConcept C2778048844 @default.
• W2093200633 hasConcept C2778371730 @default.
• W2093200633 hasConcept C2778396349 @default.
• W2093200633 hasConcept C2779716203 @default.
• W2093200633 hasConcept C55493867 @default.
• W2093200633 hasConcept C57790582 @default.
• W2093200633 hasConcept C71240020 @default.
• W2093200633 hasConcept C86803240 @default.
• W2093200633 hasConcept C98274493 @default.
• W2093200633 hasConceptScore W2093200633C181199279 @default.
• W2093200633 hasConceptScore W2093200633C185592680 @default.
• W2093200633 hasConceptScore W2093200633C202751555 @default.
• W2093200633 hasConceptScore W2093200633C203014093 @default.
• W2093200633 hasConceptScore W2093200633C2777827897 @default.
• W2093200633 hasConceptScore W2093200633C2778048844 @default.
• W2093200633 hasConceptScore W2093200633C2778371730 @default.
• W2093200633 hasConceptScore W2093200633C2778396349 @default.
• W2093200633 hasConceptScore W2093200633C2779716203 @default.
• W2093200633 hasConceptScore W2093200633C55493867 @default.
• W2093200633 hasConceptScore W2093200633C57790582 @default.
• W2093200633 hasConceptScore W2093200633C71240020 @default.
• W2093200633 hasConceptScore W2093200633C86803240 @default.
• W2093200633 hasConceptScore W2093200633C98274493 @default.
• W2093200633 hasIssue "2" @default.
• W2093200633 hasLocation W20932006331 @default.
• W2093200633 hasLocation W20932006332 @default.
• W2093200633 hasLocation W20932006333 @default.
• W2093200633 hasLocation W20932006334 @default.
• W2093200633 hasOpenAccess W2093200633 @default.
• W2093200633 hasPrimaryLocation W20932006331 @default.
• W2093200633 hasRelatedWork W1964186173 @default.
• W2093200633 hasRelatedWork W1984485872 @default.
• W2093200633 hasRelatedWork W2011345790 @default.
• W2093200633 hasRelatedWork W2025236694 @default.
• W2093200633 hasRelatedWork W2026607662 @default.
• W2093200633 hasRelatedWork W2042642416 @default.
• W2093200633 hasRelatedWork W2053288336 @default.
• W2093200633 hasRelatedWork W2103221476 @default.
• W2093200633 hasRelatedWork W2339901706 @default.
• W2093200633 hasRelatedWork W772419387 @default.
• W2093200633 hasVolume "18" @default.
• W2093200633 isParatext "false" @default.
• W2093200633 isRetracted "false" @default.
• W2093200633 magId "2093200633" @default.

• next