FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093217653> ?p ?o ?g. }

• W2093217653 endingPage "163" @default.
• W2093217653 startingPage "157" @default.
• W2093217653 abstract "Purpose New methods of measuring and controlling glycemia in diabetes mellitus have been developed and implemented in the past 10 years. We examined whether glycemia, as measured by glycosylated hemoglobin, changed in outpatient insulin-dependent diabetes mellitus (IDDM) and noninsulin-dependent diabetes mellitus (NIDDM) populations between 1985 and 1993 and whether contemporaneous changes in therapy could account for observed changes in glycemia. Patients and methods Outpatients were selected based on having glycated hemoglobin (HbA1c) measured in the Massachusetts General Hospital laboratory during March 1985 (IDDM n = 94 and NIDDM n = 137) or during March 1993 (IDDM n = 89 and NIDDM n = 118). Chart reviews established demographic and clinical characteristics, including frequency of blood glucose self-monitoring, insulin injections, office visits, and HbA1c measurements during the year prior to the HbA1c result. Results Mean HbA1c level was significantly lower in the 1993 IDDM cohort compared with the 1985 cohort (8.77% ± 1.7% versus 9.47% ± 2.1%, P = 0.014). In the NIDDM cohorts, the difference in mean HbA1c did not achieve statistical significance (8.35% ± 1.6% in 1993 versus 8.75% ± 2.1% in 1985, P = 0.09); however, when adjusted for differences in NIDDM duration, HbA1c in the 1993 cohort was significantly lower than that in the 1985 cohort. The largest decrease in HbA1c in NIDDM was in patients treated with insulin (9.53% ± 2.0% versus 8.54% ± 1.5% in 1985 and 1993, respectively, P = 0.004). Multiple linear regression analyses demonstrated that increased frequency of self-monitoring and of insulin injections were associated with lower HbA1c in IDDM. Conclusions The level of average glycemia has decreased in IDDM patients over the past 8 years, attributable, at least in part, to an increased frequency of monitoring and of insulin injections. Glycemia decreased in NIDDM, especially in the subset of patients treated with insulin. This temporal shift in glycemic control should have a salutary effect on the development of long-term microvascular and neurologic complications. New methods of measuring and controlling glycemia in diabetes mellitus have been developed and implemented in the past 10 years. We examined whether glycemia, as measured by glycosylated hemoglobin, changed in outpatient insulin-dependent diabetes mellitus (IDDM) and noninsulin-dependent diabetes mellitus (NIDDM) populations between 1985 and 1993 and whether contemporaneous changes in therapy could account for observed changes in glycemia. Outpatients were selected based on having glycated hemoglobin (HbA1c) measured in the Massachusetts General Hospital laboratory during March 1985 (IDDM n = 94 and NIDDM n = 137) or during March 1993 (IDDM n = 89 and NIDDM n = 118). Chart reviews established demographic and clinical characteristics, including frequency of blood glucose self-monitoring, insulin injections, office visits, and HbA1c measurements during the year prior to the HbA1c result. Mean HbA1c level was significantly lower in the 1993 IDDM cohort compared with the 1985 cohort (8.77% ± 1.7% versus 9.47% ± 2.1%, P = 0.014). In the NIDDM cohorts, the difference in mean HbA1c did not achieve statistical significance (8.35% ± 1.6% in 1993 versus 8.75% ± 2.1% in 1985, P = 0.09); however, when adjusted for differences in NIDDM duration, HbA1c in the 1993 cohort was significantly lower than that in the 1985 cohort. The largest decrease in HbA1c in NIDDM was in patients treated with insulin (9.53% ± 2.0% versus 8.54% ± 1.5% in 1985 and 1993, respectively, P = 0.004). Multiple linear regression analyses demonstrated that increased frequency of self-monitoring and of insulin injections were associated with lower HbA1c in IDDM. The level of average glycemia has decreased in IDDM patients over the past 8 years, attributable, at least in part, to an increased frequency of monitoring and of insulin injections. Glycemia decreased in NIDDM, especially in the subset of patients treated with insulin. This temporal shift in glycemic control should have a salutary effect on the development of long-term microvascular and neurologic complications." @default.
• W2093217653 created "2016-06-24" @default.
• W2093217653 creator A5009783259 @default.
• W2093217653 creator A5020290782 @default.
• W2093217653 creator A5025923808 @default.
• W2093217653 creator A5068910064 @default.
• W2093217653 creator A5081958574 @default.
• W2093217653 date "1996-02-01" @default.
• W2093217653 modified "2023-09-27" @default.
• W2093217653 title "Glycemic control in diabetes mellitus: have changes in therapy made a difference?" @default.
• W2093217653 cites W1964413807 @default.
• W2093217653 cites W1977761436 @default.
• W2093217653 cites W1979386588 @default.
• W2093217653 cites W1982809596 @default.
• W2093217653 cites W2010456451 @default.
• W2093217653 cites W2015904026 @default.
• W2093217653 cites W2026718145 @default.
• W2093217653 cites W2031598718 @default.
• W2093217653 cites W2083072605 @default.
• W2093217653 cites W2084308090 @default.
• W2093217653 cites W2091425245 @default.
• W2093217653 cites W2151799675 @default.
• W2093217653 cites W2161681956 @default.
• W2093217653 cites W2322920882 @default.
• W2093217653 cites W2769264260 @default.
• W2093217653 cites W4214774002 @default.
• W2093217653 doi "https://doi.org/10.1016/s0002-9343(97)89453-3" @default.
• W2093217653 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8629649" @default.
• W2093217653 hasPublicationYear "1996" @default.
• W2093217653 type Work @default.
• W2093217653 sameAs 2093217653 @default.
• W2093217653 citedByCount "75" @default.
• W2093217653 countsByYear W20932176532012 @default.
• W2093217653 countsByYear W20932176532013 @default.
• W2093217653 countsByYear W20932176532014 @default.
• W2093217653 countsByYear W20932176532015 @default.
• W2093217653 countsByYear W20932176532016 @default.
• W2093217653 countsByYear W20932176532018 @default.
• W2093217653 countsByYear W20932176532022 @default.
• W2093217653 crossrefType "journal-article" @default.
• W2093217653 hasAuthorship W2093217653A5009783259 @default.
• W2093217653 hasAuthorship W2093217653A5020290782 @default.
• W2093217653 hasAuthorship W2093217653A5025923808 @default.
• W2093217653 hasAuthorship W2093217653A5068910064 @default.
• W2093217653 hasAuthorship W2093217653A5081958574 @default.
• W2093217653 hasConcept C126322002 @default.
• W2093217653 hasConcept C134018914 @default.
• W2093217653 hasConcept C201903717 @default.
• W2093217653 hasConcept C2777180221 @default.
• W2093217653 hasConcept C2777393523 @default.
• W2093217653 hasConcept C2777538456 @default.
• W2093217653 hasConcept C2778917026 @default.
• W2093217653 hasConcept C2779306644 @default.
• W2093217653 hasConcept C2780473172 @default.
• W2093217653 hasConcept C555293320 @default.
• W2093217653 hasConcept C70818257 @default.
• W2093217653 hasConcept C71924100 @default.
• W2093217653 hasConcept C72563966 @default.
• W2093217653 hasConceptScore W2093217653C126322002 @default.
• W2093217653 hasConceptScore W2093217653C134018914 @default.
• W2093217653 hasConceptScore W2093217653C201903717 @default.
• W2093217653 hasConceptScore W2093217653C2777180221 @default.
• W2093217653 hasConceptScore W2093217653C2777393523 @default.
• W2093217653 hasConceptScore W2093217653C2777538456 @default.
• W2093217653 hasConceptScore W2093217653C2778917026 @default.
• W2093217653 hasConceptScore W2093217653C2779306644 @default.
• W2093217653 hasConceptScore W2093217653C2780473172 @default.
• W2093217653 hasConceptScore W2093217653C555293320 @default.
• W2093217653 hasConceptScore W2093217653C70818257 @default.
• W2093217653 hasConceptScore W2093217653C71924100 @default.
• W2093217653 hasConceptScore W2093217653C72563966 @default.
• W2093217653 hasIssue "2" @default.
• W2093217653 hasLocation W20932176531 @default.
• W2093217653 hasLocation W20932176532 @default.
• W2093217653 hasOpenAccess W2093217653 @default.
• W2093217653 hasPrimaryLocation W20932176531 @default.
• W2093217653 hasRelatedWork W1983641721 @default.
• W2093217653 hasRelatedWork W1995945960 @default.
• W2093217653 hasRelatedWork W2026226896 @default.
• W2093217653 hasRelatedWork W2031598718 @default.
• W2093217653 hasRelatedWork W2066345847 @default.
• W2093217653 hasRelatedWork W2093217653 @default.
• W2093217653 hasRelatedWork W2095179743 @default.
• W2093217653 hasRelatedWork W2401900718 @default.
• W2093217653 hasRelatedWork W2517384154 @default.
• W2093217653 hasRelatedWork W3006078599 @default.
• W2093217653 hasVolume "100" @default.
• W2093217653 isParatext "false" @default.
• W2093217653 isRetracted "false" @default.
• W2093217653 magId "2093217653" @default.
• W2093217653 workType "article" @default.