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- W2093232886 abstract "PURPOSE To compare the changes in claudication pain, ambulatory function, daily physical activity, peripheral circulation, and health-related quality of life following a program of exercise rehabilitation in smoking and non-smoking patients with peripheral arterial disease (PAD) limited by intermittent claudication. METHODS Thirty-nine smokers (63 ± 4 pack-year smoking history; mean ± SE) and 46 non-smokers (former smokers who had a 51 ± 7 pack-year smoking history who quit 14 ± 2 years priorto investigation) completed the study. The 6-month exercise rehabilitation program consisted of intermittent treadmill walking to near maximal claudication pain three days per week, with progressive increases in walking duration and intensity during the program. RESULTS At baseline, the smokers had impaired (p <0.05) claudication pain, ambulatory function, daily physical activity, peripheral circulation, and health-related quality of life compared to the non-smokers. Following exercise rehabilitation, initial claudication distance increased by 119% in the smokers (p <0.001) and by 97% in the non-smokers (p <0.001), and absolute claudication distance increased by 82% (p <0.001) and 59% (p <0.001) in the smokers and non-smokers, respectively. Furthermore, exercise rehabilitation improved (p <0.05) ambulatory function, daily physical activity, peripheral circulation, and health-related quality of life in the smokers and non-smokers. All of the changes following the exercise rehabilitation program were similar between the two groups. CONCLUSION Exercise rehabilitation is an effective therapy to improve functional independence in both smoking and non-smoking PAD patients limited by intermittent claudication. Therefore, smokers with intermittent claudication are prime candidates for exercise rehabilitation because their relatively low baseline physical function does not impair their ability to regain lost functional independence to levels similar to non-smoking PAD patients." @default.
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- W2093232886 date "2003-05-01" @default.
- W2093232886 modified "2023-10-18" @default.
- W2093232886 title "THE RESPONSE TO EXERCISE REHABILITATION IN SMOKING AND NON-SMOKING PATIENTS WITH INTERMITTENT CLAUDICATION" @default.
- W2093232886 doi "https://doi.org/10.1097/00005768-200305001-01282" @default.
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