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- W2093240504 endingPage "251" @default.
- W2093240504 startingPage "235" @default.
- W2093240504 abstract "Clinical practice in psychiatry suffers from a lack of objective measures that could complement the clinical evaluation of the patient. The search for peripheral markers reflecting psychiatric disease state and trait has been under constant scrutiny for a few decades and numerous candidates have been tested based on several disease pathogenesis hypotheses. However, the results have often been of poor outcome or not replicable. Recent developments in proteomic and genomic approaches are expanding the number of testable hypotheses by some orders of magnitude and are allowing for the identification of patterns or signatures, rather than single markers, thus creating the premises for a paradigm shift in the search for biomarkers in psychiatry. A series of studies documenting the potential offered by large-scale transcription analyses and proteomic profiling in a number of psychiatric disorders are reported in this review. Specific applications of microarrays to CNS disorders to generate blood-derived disease signatures are discussed. Future progresses in genome- and proteome-wide investigations of peripheral samples and their integration with genetic and imaging studies will increase the chance of identifying non-invasive diagnostic tests providing clinicians with an integrated biological view of the psychiatric patients." @default.
- W2093240504 created "2016-06-24" @default.
- W2093240504 creator A5009295406 @default.
- W2093240504 creator A5050995972 @default.
- W2093240504 date "2007-10-01" @default.
- W2093240504 modified "2023-10-16" @default.
- W2093240504 title "The search for peripheral disease markers in psychiatry by genomic and proteomic approaches" @default.
- W2093240504 cites W144869126 @default.
- W2093240504 cites W1528656348 @default.
- W2093240504 cites W1732798991 @default.
- W2093240504 cites W1966075614 @default.
- W2093240504 cites W1966821526 @default.
- W2093240504 cites W1967053372 @default.
- W2093240504 cites W1968213313 @default.
- W2093240504 cites W1970988969 @default.
- W2093240504 cites W1971606140 @default.
- W2093240504 cites W1973271647 @default.
- W2093240504 cites W1973985650 @default.
- W2093240504 cites W1976182760 @default.
- W2093240504 cites W1979039874 @default.
- W2093240504 cites W1979227761 @default.
- W2093240504 cites W1979521995 @default.
- W2093240504 cites W1980719669 @default.
- W2093240504 cites W1985477682 @default.
- W2093240504 cites W1986720623 @default.
- W2093240504 cites W1991049734 @default.
- W2093240504 cites W1993183966 @default.
- W2093240504 cites W1993365011 @default.
- W2093240504 cites W1993668812 @default.
- W2093240504 cites W1994294365 @default.
- W2093240504 cites W1994717855 @default.
- W2093240504 cites W1996207491 @default.
- W2093240504 cites W1999369934 @default.
- W2093240504 cites W1999682854 @default.
- W2093240504 cites W2000299221 @default.
- W2093240504 cites W2000980666 @default.
- W2093240504 cites W2005445084 @default.
- W2093240504 cites W2005445859 @default.
- W2093240504 cites W2010316443 @default.
- W2093240504 cites W2011080454 @default.
- W2093240504 cites W2013389390 @default.
- W2093240504 cites W2014606320 @default.
- W2093240504 cites W2015579602 @default.
- W2093240504 cites W2016441589 @default.
- W2093240504 cites W2018823764 @default.
- W2093240504 cites W2019635065 @default.
- W2093240504 cites W2019781881 @default.
- W2093240504 cites W2020983914 @default.
- W2093240504 cites W2023708482 @default.
- W2093240504 cites W2025240330 @default.
- W2093240504 cites W2025922556 @default.
- W2093240504 cites W2026131598 @default.
- W2093240504 cites W2034150569 @default.
- W2093240504 cites W2034194523 @default.
- W2093240504 cites W2035141606 @default.
- W2093240504 cites W2039142214 @default.
- W2093240504 cites W2039399819 @default.
- W2093240504 cites W2039517305 @default.
- W2093240504 cites W2039636801 @default.
- W2093240504 cites W2040933142 @default.
- W2093240504 cites W2042473905 @default.
- W2093240504 cites W2042564093 @default.
- W2093240504 cites W2044047532 @default.
- W2093240504 cites W2044325685 @default.
- W2093240504 cites W2044514969 @default.
- W2093240504 cites W2045355179 @default.
- W2093240504 cites W2049373941 @default.
- W2093240504 cites W2050062456 @default.
- W2093240504 cites W2050601953 @default.
- W2093240504 cites W2051698476 @default.
- W2093240504 cites W2051822945 @default.
- W2093240504 cites W2054985002 @default.
- W2093240504 cites W2055747883 @default.
- W2093240504 cites W2057339543 @default.
- W2093240504 cites W2057459426 @default.
- W2093240504 cites W2061567983 @default.
- W2093240504 cites W2064433644 @default.
- W2093240504 cites W2067245109 @default.
- W2093240504 cites W2068867623 @default.
- W2093240504 cites W2071359982 @default.
- W2093240504 cites W2076717018 @default.
- W2093240504 cites W2079758559 @default.
- W2093240504 cites W2080560162 @default.
- W2093240504 cites W2081341956 @default.
- W2093240504 cites W2088736589 @default.
- W2093240504 cites W2088751222 @default.
- W2093240504 cites W2090348783 @default.
- W2093240504 cites W2091576663 @default.
- W2093240504 cites W2091627651 @default.
- W2093240504 cites W2093150481 @default.
- W2093240504 cites W2093360069 @default.
- W2093240504 cites W2094608167 @default.
- W2093240504 cites W2097254597 @default.
- W2093240504 cites W2098616868 @default.
- W2093240504 cites W2100122916 @default.
- W2093240504 cites W2113193134 @default.
- W2093240504 cites W2113354422 @default.
- W2093240504 cites W2115039568 @default.