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• W2093254257 abstract "Polyamine toxins isolated from the venoms of spiders and wasps and their synthetic analogues are uncompetitive antagonists of ligand-gated ionotropic receptors in the central- and peripheral nervous systems, and have proved valuable as tools for the investigation of receptor structure and function. In the present letter we describe the efficient solid-phase synthesis (SPS) of novel hybrid toxins using a BAL resin. This strategy enables the bidirectional construction of toxin molecules and has a potential in SPS of chemically diverse libraries of toxin analogues for structure–activity relationship (SAR) studies." @default.
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• W2093254257 date "2007-01-01" @default.
• W2093254257 modified "2023-10-17" @default.
• W2093254257 title "Solid-phase synthesis of neuroactive spider–wasp hybrid toxin analogues using a backbone amide linker" @default.
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• W2093254257 doi "https://doi.org/10.1016/j.tetlet.2006.11.074" @default.
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