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• W2093272023 abstract "To evaluate the current literature about the efficacy of providing inhaled medications by metered-dose inhalers and accessory devices (MDI/ADs) to children with acute asthma and to compare it with the current standard of care, small-volume nebulizers (SVNs).Online computer and manual searches in English-language journal articles published between 1980 and 1996.Seventeen prospective clinical trials that have used MDI/ADs in the treatment of acute asthma in children were retrieved. Ten randomized controlled studies that included a comparison with SVN treatment were selected.Studies were assessed qualitatively by their subject characteristics, design, intervention procedures, outcome measures, and results.There were marked variations in types of MDI/ADs and in doses administered between and within studies. Major outcome measures included pulmonary function measurements and clinical scores. All studies found MDI/ADs to be effective in the treatment of infants and children with acute asthma. Among those who compared this treatment with SVN, 2 found the MDI/AD superior and the rest found it as effective as the SVN.The data support the effectiveness of MDI/ADs as first-line treatment in acute childhood asthma. In view of clinical benefit, safety, lower cost, personnel time, and speed and ease of administration of MDI/ADs compared with SVNs, MDI/ADs should be considered the preferred mode of treatment of children with acute asthma." @default.
• W2093272023 created "2016-06-24" @default.
• W2093272023 creator A5029172221 @default.
• W2093272023 date "1997-09-01" @default.
• W2093272023 modified "2023-10-18" @default.
• W2093272023 title "Metered-Dose Inhaler Accessory Devices in Acute Asthma" @default.
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• W2093272023 doi "https://doi.org/10.1001/archpedi.1997.02170460014003" @default.
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