Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093281894> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2093281894 endingPage "185" @default.
- W2093281894 startingPage "176" @default.
- W2093281894 abstract "Histologic distinction between complete hydatidiform moles and nonmolar abortuses in early pregnancy is often extremely difficult. This study details the chronologic changes that occur in normal placenta, especially in the villous stroma during gestational weeks 4 to 12 and compares the findings in 63 normal placentas and 73 early complete moles. Over time, the chorionic villi in normal placenta showed gradual but recognizable alterations, from basophilic/hypocellular and nonvascular stroma to basophilic/cellular stroma containing angiogenic cell cords (immature blood vessels), and then to loose, edematous/reticular stroma with mature blood vessels containing vascular lumina and hematopoietic components. A basophilic stroma, which was frequently seen in early complete moles, was a constant feature of chorionic villi younger than week 7 in normal placenta, but had disappeared after week 8, except in the newly branched sprouts. Trophoblastic proliferation was virtually unrecognizable in 59% of early complete moles, whereas circumferential trophoblastic sprouts during weeks 4 to 6 of normal placenta can be mistaken as that of complete moles. Few or no mature blood vessels and excessive stromal karyorrhexis are characteristic features of early complete moles, even in the absence of trophoblastic proliferation, but they are occasionally found in normal placenta younger than week 7. Although many features of normal and molar placenta were similar during the earliest weeks (5 to 6) including basophilic stroma, angiogenic cell cords (immature blood vessels), and often circumferential trophoblastic sprouts and proliferation, already by that time early moles showed significantly greater percentages of stromal cells undergoing karyorrhexis and apoptosis compared with normal placenta (37.6% vs. 5.4%). These results indicate the histologic features do exist early on in pregnancy to differentiate normal from molar pregnancy. Further, it points out that complete hydatidiform mole in addition to being disease of trophoblastic proliferation is also associated with defects in vasculogenesis and maturation of villous stromal constituents." @default.
- W2093281894 created "2016-06-24" @default.
- W2093281894 creator A5005144703 @default.
- W2093281894 creator A5013321556 @default.
- W2093281894 creator A5040364168 @default.
- W2093281894 creator A5042609752 @default.
- W2093281894 creator A5073990103 @default.
- W2093281894 date "2009-02-01" @default.
- W2093281894 modified "2023-09-27" @default.
- W2093281894 title "The Villous Stromal Constituents of Complete Hydatidiform Mole Differ Histologically in Very Early Pregnancy From the Normally Developing Placenta" @default.
- W2093281894 cites W1964565886 @default.
- W2093281894 cites W1974926045 @default.
- W2093281894 cites W1987356810 @default.
- W2093281894 cites W2001082893 @default.
- W2093281894 cites W2007736906 @default.
- W2093281894 cites W2011569892 @default.
- W2093281894 cites W2027243767 @default.
- W2093281894 cites W2037086921 @default.
- W2093281894 cites W2053744839 @default.
- W2093281894 cites W2077308783 @default.
- W2093281894 cites W2098887960 @default.
- W2093281894 cites W2103545541 @default.
- W2093281894 cites W2116798645 @default.
- W2093281894 cites W59564054 @default.
- W2093281894 doi "https://doi.org/10.1097/pas.0b013e31817fada1" @default.
- W2093281894 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18936691" @default.
- W2093281894 hasPublicationYear "2009" @default.
- W2093281894 type Work @default.
- W2093281894 sameAs 2093281894 @default.
- W2093281894 citedByCount "14" @default.
- W2093281894 countsByYear W20932818942012 @default.
- W2093281894 countsByYear W20932818942013 @default.
- W2093281894 countsByYear W20932818942014 @default.
- W2093281894 countsByYear W20932818942015 @default.
- W2093281894 countsByYear W20932818942017 @default.
- W2093281894 countsByYear W20932818942019 @default.
- W2093281894 countsByYear W20932818942020 @default.
- W2093281894 crossrefType "journal-article" @default.
- W2093281894 hasAuthorship W2093281894A5005144703 @default.
- W2093281894 hasAuthorship W2093281894A5013321556 @default.
- W2093281894 hasAuthorship W2093281894A5040364168 @default.
- W2093281894 hasAuthorship W2093281894A5042609752 @default.
- W2093281894 hasAuthorship W2093281894A5073990103 @default.
- W2093281894 hasConcept C142724271 @default.
- W2093281894 hasConcept C16685009 @default.
- W2093281894 hasConcept C16930146 @default.
- W2093281894 hasConcept C172680121 @default.
- W2093281894 hasConcept C190283241 @default.
- W2093281894 hasConcept C19210678 @default.
- W2093281894 hasConcept C204232928 @default.
- W2093281894 hasConcept C206631613 @default.
- W2093281894 hasConcept C2776953305 @default.
- W2093281894 hasConcept C2779234561 @default.
- W2093281894 hasConcept C2781385326 @default.
- W2093281894 hasConcept C31573885 @default.
- W2093281894 hasConcept C52124034 @default.
- W2093281894 hasConcept C54355233 @default.
- W2093281894 hasConcept C55493867 @default.
- W2093281894 hasConcept C71924100 @default.
- W2093281894 hasConcept C86803240 @default.
- W2093281894 hasConceptScore W2093281894C142724271 @default.
- W2093281894 hasConceptScore W2093281894C16685009 @default.
- W2093281894 hasConceptScore W2093281894C16930146 @default.
- W2093281894 hasConceptScore W2093281894C172680121 @default.
- W2093281894 hasConceptScore W2093281894C190283241 @default.
- W2093281894 hasConceptScore W2093281894C19210678 @default.
- W2093281894 hasConceptScore W2093281894C204232928 @default.
- W2093281894 hasConceptScore W2093281894C206631613 @default.
- W2093281894 hasConceptScore W2093281894C2776953305 @default.
- W2093281894 hasConceptScore W2093281894C2779234561 @default.
- W2093281894 hasConceptScore W2093281894C2781385326 @default.
- W2093281894 hasConceptScore W2093281894C31573885 @default.
- W2093281894 hasConceptScore W2093281894C52124034 @default.
- W2093281894 hasConceptScore W2093281894C54355233 @default.
- W2093281894 hasConceptScore W2093281894C55493867 @default.
- W2093281894 hasConceptScore W2093281894C71924100 @default.
- W2093281894 hasConceptScore W2093281894C86803240 @default.
- W2093281894 hasIssue "2" @default.
- W2093281894 hasLocation W20932818941 @default.
- W2093281894 hasLocation W20932818942 @default.
- W2093281894 hasOpenAccess W2093281894 @default.
- W2093281894 hasPrimaryLocation W20932818941 @default.
- W2093281894 hasRelatedWork W2013760228 @default.
- W2093281894 hasRelatedWork W2093281894 @default.
- W2093281894 hasRelatedWork W2098923832 @default.
- W2093281894 hasRelatedWork W2303040396 @default.
- W2093281894 hasRelatedWork W2409645704 @default.
- W2093281894 hasRelatedWork W2412122492 @default.
- W2093281894 hasRelatedWork W2412331223 @default.
- W2093281894 hasRelatedWork W2413410370 @default.
- W2093281894 hasRelatedWork W2422399853 @default.
- W2093281894 hasRelatedWork W2809225164 @default.
- W2093281894 hasVolume "33" @default.
- W2093281894 isParatext "false" @default.
- W2093281894 isRetracted "false" @default.
- W2093281894 magId "2093281894" @default.
- W2093281894 workType "article" @default.