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- W2093295536 abstract "Cholinesterase inhibition is considered a specific biomarker of exposure and effect for organophosphorous pesticides. Its use for monitoring has been hindered, particularly in tropical countries where organophosphates are widely used for malaria and dengue control, because of the frequent lack of suitable controls. An in vitro technique is proposed as a biochemical method for monitoring pollutant mixtures in sediment toxicity tests. Brain homogenate from the fish Oreochromis niloticus is used as the enzyme source. Optimum incubation time, extraction solvent and effect of crude oil on acetylcholinesterase (AChE) are reported. The method described was used in sediments from two Mexican lagoons, located in an oil extraction area where pesticides are used in agriculture and vector control campaigns. AChE inhibitions from 3 to 21% were found in these lagoons, even in the presence of high concentrations of petroleum." @default.
- W2093295536 created "2016-06-24" @default.
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- W2093295536 date "2000-07-01" @default.
- W2093295536 modified "2023-10-06" @default.
- W2093295536 title "Environmental monitoring using acetylcholinesterase inhibition in vitro. A case study in two Mexican lagoons" @default.
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- W2093295536 doi "https://doi.org/10.1016/s0141-1136(00)00062-3" @default.
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