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• W2093314395 abstract "The purpose of this study was to evaluate the effects of interleukin-13 (IL-13) polymorphisms on the risk of asthma using a meta-analysis.Fifteen publications were identified by searching Pubmed, Embase, ISI, OVID, and EBSCO databases. Odds ratios with corresponding 95% confidence intervals were computed to estimate the association between IL-13 polymorphisms and risk of asthma.The polymorphisms of R130Q (rs20541) and -1112C/T (rs1800925) in IL-13 gene were associated with significantly increased risks of asthma in overall analyses. Subgroup analyses showed that the elevated risks occurred in adult-onset asthma, Caucasians, and high quality studies.This meta-analysis provides evidence that the R130Q and -1112C/T polymorphisms in IL-13 are risk factors for asthma." @default.
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• W2093314395 date "2012-03-01" @default.
• W2093314395 modified "2023-09-29" @default.
• W2093314395 title "IL-13 polymorphisms contribute to the risk of asthma: A meta-analysis" @default.
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• W2093314395 doi "https://doi.org/10.1016/j.clinbiochem.2011.12.012" @default.
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