Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093350265> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2093350265 endingPage "174" @default.
- W2093350265 startingPage "165" @default.
- W2093350265 abstract "Genes can be associated with disease through an individual’s inherited genotype, the maternal genotype or the interaction between these two. When the gene is highly polymorphic, it is more difficult to identify the gene’s functional role than for less polymorphic loci, because different alleles at the locus may be associated with the disease through separate and joint effects from maternal and offspring genotypes. Family-based studies are used to test genetic associations because of their robustness to population stratification. However, parental genotype data are often missing, and omitting incompletely genotyped families is inefficient. Methods have been proposed to accommodate incomplete families in family-based association studies. They are not easily generalized to allow simultaneous examination of offspring allelic, maternal allelic and maternal-fetal genotype (MFG) incompatibility effects. Since many MFG incompatibility effects occur through matching between maternal and offspring’s genotypes, we present an identity-by-state (IBS) framework to incorporate incomplete families in the MFG test when modeling genetic effects produced by a polymorphic gene. Using simulations, we examine the MFG test’s performance with incomplete parental genotype data and an IBS framework. The MFG test using the IBS framework is immune to population stratification and efficiently uses information from incomplete families." @default.
- W2093350265 created "2016-06-24" @default.
- W2093350265 creator A5013824247 @default.
- W2093350265 creator A5052860956 @default.
- W2093350265 creator A5069400265 @default.
- W2093350265 date "2006-01-01" @default.
- W2093350265 modified "2023-09-23" @default.
- W2093350265 title "Allowing for Missing Data at Highly Polymorphic Genes when Testing for Maternal, Offspring and Maternal-Fetal Genotype Incompatibility Effects" @default.
- W2093350265 cites W1971331002 @default.
- W2093350265 cites W1975752242 @default.
- W2093350265 cites W1984308143 @default.
- W2093350265 cites W1990985972 @default.
- W2093350265 cites W1993469491 @default.
- W2093350265 cites W2029784047 @default.
- W2093350265 cites W2032256811 @default.
- W2093350265 cites W2052071194 @default.
- W2093350265 cites W2054980981 @default.
- W2093350265 cites W2064978607 @default.
- W2093350265 cites W2071411739 @default.
- W2093350265 cites W2080167581 @default.
- W2093350265 cites W2081044490 @default.
- W2093350265 cites W2098349425 @default.
- W2093350265 cites W2104114526 @default.
- W2093350265 cites W2105281841 @default.
- W2093350265 cites W2106004488 @default.
- W2093350265 cites W2124450131 @default.
- W2093350265 cites W2124706227 @default.
- W2093350265 cites W2132656320 @default.
- W2093350265 cites W2132685183 @default.
- W2093350265 cites W2134156548 @default.
- W2093350265 cites W2161929126 @default.
- W2093350265 cites W2480680997 @default.
- W2093350265 cites W4229628595 @default.
- W2093350265 doi "https://doi.org/10.1159/000096444" @default.
- W2093350265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17065817" @default.
- W2093350265 hasPublicationYear "2006" @default.
- W2093350265 type Work @default.
- W2093350265 sameAs 2093350265 @default.
- W2093350265 citedByCount "12" @default.
- W2093350265 countsByYear W20933502652012 @default.
- W2093350265 countsByYear W20933502652013 @default.
- W2093350265 countsByYear W20933502652014 @default.
- W2093350265 crossrefType "journal-article" @default.
- W2093350265 hasAuthorship W2093350265A5013824247 @default.
- W2093350265 hasAuthorship W2093350265A5052860956 @default.
- W2093350265 hasAuthorship W2093350265A5069400265 @default.
- W2093350265 hasConcept C104317684 @default.
- W2093350265 hasConcept C112672928 @default.
- W2093350265 hasConcept C135763542 @default.
- W2093350265 hasConcept C153209595 @default.
- W2093350265 hasConcept C166976648 @default.
- W2093350265 hasConcept C180754005 @default.
- W2093350265 hasConcept C186413461 @default.
- W2093350265 hasConcept C197754878 @default.
- W2093350265 hasConcept C2776885448 @default.
- W2093350265 hasConcept C2779234561 @default.
- W2093350265 hasConcept C2908647359 @default.
- W2093350265 hasConcept C54355233 @default.
- W2093350265 hasConcept C71924100 @default.
- W2093350265 hasConcept C84597430 @default.
- W2093350265 hasConcept C86803240 @default.
- W2093350265 hasConcept C99454951 @default.
- W2093350265 hasConceptScore W2093350265C104317684 @default.
- W2093350265 hasConceptScore W2093350265C112672928 @default.
- W2093350265 hasConceptScore W2093350265C135763542 @default.
- W2093350265 hasConceptScore W2093350265C153209595 @default.
- W2093350265 hasConceptScore W2093350265C166976648 @default.
- W2093350265 hasConceptScore W2093350265C180754005 @default.
- W2093350265 hasConceptScore W2093350265C186413461 @default.
- W2093350265 hasConceptScore W2093350265C197754878 @default.
- W2093350265 hasConceptScore W2093350265C2776885448 @default.
- W2093350265 hasConceptScore W2093350265C2779234561 @default.
- W2093350265 hasConceptScore W2093350265C2908647359 @default.
- W2093350265 hasConceptScore W2093350265C54355233 @default.
- W2093350265 hasConceptScore W2093350265C71924100 @default.
- W2093350265 hasConceptScore W2093350265C84597430 @default.
- W2093350265 hasConceptScore W2093350265C86803240 @default.
- W2093350265 hasConceptScore W2093350265C99454951 @default.
- W2093350265 hasIssue "3" @default.
- W2093350265 hasLocation W20933502651 @default.
- W2093350265 hasLocation W20933502652 @default.
- W2093350265 hasOpenAccess W2093350265 @default.
- W2093350265 hasPrimaryLocation W20933502651 @default.
- W2093350265 hasRelatedWork W1543069114 @default.
- W2093350265 hasRelatedWork W1970327593 @default.
- W2093350265 hasRelatedWork W2021805308 @default.
- W2093350265 hasRelatedWork W2044301617 @default.
- W2093350265 hasRelatedWork W2057739827 @default.
- W2093350265 hasRelatedWork W2143408077 @default.
- W2093350265 hasRelatedWork W2187386201 @default.
- W2093350265 hasRelatedWork W2355023196 @default.
- W2093350265 hasRelatedWork W2393464409 @default.
- W2093350265 hasRelatedWork W64331312 @default.
- W2093350265 hasVolume "62" @default.
- W2093350265 isParatext "false" @default.
- W2093350265 isRetracted "false" @default.
- W2093350265 magId "2093350265" @default.
- W2093350265 workType "article" @default.