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- W2093376189 abstract "Abstract To elucidate the involvement of motor pathways in konzo, 21 konzo subjects (mean age 22 years) underwent transcranial electrical stimulation (TES) in 1998. Fourteen konzo subjects (mean age 21 years) underwent transcranial magnetic stimulation (TMS) in 2000. Three subjects underwent both TES and TMS. Motor evoked potentials (MEPs) were recorded in the abductor pollicis brevis (APB) muscle with TES, and in the abductor digiti minimi (ADM) and tibialis anterior (TA) muscles with TMS. APB‐MEPs were normal in 2 of 21 subjects and absent in 9; central conduction time (CCT) was prolonged in 10. Resting ADM‐MEPs were absent in 9 of 14 subjects with clinically preserved upper limbs. Among these nine, seven subjects responded after facilitation. Most subjects (13 of 14) failed to show TA‐MEPs. Of the subjects who underwent both types of stimulation, one had normal TES‐MEP but abnormal ADM‐MEP with TMS. These findings suggest involvement of both corticomotoneurons and motor descending pathways in konzo. © 2002 John Wiley & Sons, Inc. Muscle Nerve 25: 230–235, 2002 DOI 10.1002/mus.10029" @default.
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- W2093376189 date "2002-01-28" @default.
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- W2093376189 title "Analysis of motor pathway involvement in konzo using transcranial electrical and magnetic stimulation" @default.
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- W2093376189 doi "https://doi.org/10.1002/mus.10029" @default.
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