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• W2093377158 abstract "Recruitment and nodule management are critical issues of lung cancer screening with low-dose computed tomography (LDCT). We report subjects' compliance and results of LDCT screening and management protocol in the active arm of the ITALUNG trial.Three thousand two hundred six smokers or former smokers invited by mail were randomized to receive four annual LDCT (n = 1613) or usual care (n = 1593). Management protocol included follow-up LDCT, 2-[18F]fluoro-2-deoxy-D glucose positron emission tomography (FDG-PET), and CT-guided fine-needle aspiration biopsy (FNAB).One thousand four hundred six subjects (87%) underwent baseline LDCT, and 1263 (79%) completed four screening rounds. LDCT was positive in 30.3% of the subjects at baseline and 15.8% subsequently. Twenty-one lung tumors in 20 subjects (1.5% detection) were found at baseline, and 20 lung tumors in 18 subjects (0.5% detection) in subsequent screening rounds. Ten of 18 prevalent (55%) and 13 of 17 incident (76%) non-small-cell cancers were in stage I. Interval growth enabled diagnosis of lung cancer in 16 subjects (42%), but at least one follow-up LDCT was obtained in 741 subjects (52.7%) over the screening period. FDG-PET obtained in 6.5% of subjects had 84% sensitivity and 90% specificity for malignant lesions. FNAB obtained in 2.4% of subjects showed 90% sensitivity and 88% specificity. Positivity of both FDG-PET and FNAB invariably predicted malignancy. Surgery for benign lesions was performed on four subjects (10% of procedures) but followed protocol violations on three subjects.High-risk subjects recruited by mail who entered LDCT screening showed a high and stable compliance. Efficacy of screening is, however, weakened by low detection rate and specificity. Adhesion to management protocol might lessen surgery for benign lesions." @default.
• W2093377158 created "2016-06-24" @default.
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• W2093377158 date "2013-07-01" @default.
• W2093377158 modified "2023-10-16" @default.
• W2093377158 title "Four-Year Results of Low-Dose CT Screening and Nodule Management in the ITALUNG Trial" @default.
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• W2093377158 cites W1933844433 @default.
• W2093377158 cites W1968664752 @default.
• W2093377158 cites W1969900098 @default.
• W2093377158 cites W1978613158 @default.
• W2093377158 cites W1983062238 @default.
• W2093377158 cites W1984956583 @default.
• W2093377158 cites W1985033899 @default.
• W2093377158 cites W1988014376 @default.
• W2093377158 cites W1990651721 @default.
• W2093377158 cites W1991563667 @default.
• W2093377158 cites W1994332379 @default.
• W2093377158 cites W2002407603 @default.
• W2093377158 cites W2008520728 @default.
• W2093377158 cites W2011515611 @default.
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• W2093377158 cites W2018404797 @default.
• W2093377158 cites W2024533694 @default.
• W2093377158 cites W2031827337 @default.
• W2093377158 cites W2031881519 @default.
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• W2093377158 cites W2075179292 @default.
• W2093377158 cites W2077845643 @default.
• W2093377158 cites W2080448710 @default.
• W2093377158 cites W2081933348 @default.
• W2093377158 cites W2089752509 @default.
• W2093377158 cites W2096762792 @default.
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• W2093377158 cites W2141128443 @default.
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• W2093377158 cites W2169863512 @default.
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• W2093377158 doi "https://doi.org/10.1097/jto.0b013e31828f68d6" @default.
• W2093377158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23612465" @default.
• W2093377158 hasPublicationYear "2013" @default.
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