Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093404230> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2093404230 endingPage "155" @default.
- W2093404230 startingPage "147" @default.
- W2093404230 abstract "The metabolism of zebularine (NSC 309132), a novel agent that inhibits DNA methyltransferases, is still uncharacterized. To examine the in vivo metabolism of zebularine, an analytical method was developed and validated (based on FDA guidelines) to quantitate 2-[(14)C]-zebularine and its major metabolites in murine plasma. Zebularine and its metabolites uridine, uracil and dihydrouracil were baseline-separated based on hydrophilic interaction chromatography by using an amino column. The assay was accurate and precise in the concentration ranges of 5.0-100 microg/mL for zebularine, 2.5-50 microg/mL for uridine, 1.0-10 microg/mL for uracil and 0.5-5.0 microg/mL for dihydrouracil. This assay is being used to quantitate zebularine and its metabolites in ongoing pharmacokinetic studies of zebularine." @default.
- W2093404230 created "2016-06-24" @default.
- W2093404230 creator A5025873983 @default.
- W2093404230 creator A5030889960 @default.
- W2093404230 creator A5034690406 @default.
- W2093404230 creator A5050962932 @default.
- W2093404230 creator A5052340302 @default.
- W2093404230 date "2006-02-01" @default.
- W2093404230 modified "2023-10-09" @default.
- W2093404230 title "Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detection" @default.
- W2093404230 cites W1987929588 @default.
- W2093404230 cites W2007470097 @default.
- W2093404230 cites W2033378658 @default.
- W2093404230 cites W2050359740 @default.
- W2093404230 cites W2055722183 @default.
- W2093404230 cites W2065782393 @default.
- W2093404230 cites W2083535257 @default.
- W2093404230 cites W2099166288 @default.
- W2093404230 cites W2111041465 @default.
- W2093404230 cites W2158582055 @default.
- W2093404230 doi "https://doi.org/10.1016/j.jchromb.2005.11.048" @default.
- W2093404230 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16364698" @default.
- W2093404230 hasPublicationYear "2006" @default.
- W2093404230 type Work @default.
- W2093404230 sameAs 2093404230 @default.
- W2093404230 citedByCount "12" @default.
- W2093404230 countsByYear W20934042302012 @default.
- W2093404230 countsByYear W20934042302016 @default.
- W2093404230 countsByYear W20934042302017 @default.
- W2093404230 crossrefType "journal-article" @default.
- W2093404230 hasAuthorship W2093404230A5025873983 @default.
- W2093404230 hasAuthorship W2093404230A5030889960 @default.
- W2093404230 hasAuthorship W2093404230A5034690406 @default.
- W2093404230 hasAuthorship W2093404230A5050962932 @default.
- W2093404230 hasAuthorship W2093404230A5052340302 @default.
- W2093404230 hasConcept C104317684 @default.
- W2093404230 hasConcept C150903083 @default.
- W2093404230 hasConcept C179998833 @default.
- W2093404230 hasConcept C181199279 @default.
- W2093404230 hasConcept C185592680 @default.
- W2093404230 hasConcept C207001950 @default.
- W2093404230 hasConcept C2777477808 @default.
- W2093404230 hasConcept C2779554091 @default.
- W2093404230 hasConcept C2781184954 @default.
- W2093404230 hasConcept C2781259782 @default.
- W2093404230 hasConcept C33288867 @default.
- W2093404230 hasConcept C43617362 @default.
- W2093404230 hasConcept C552990157 @default.
- W2093404230 hasConcept C55493867 @default.
- W2093404230 hasConcept C67705224 @default.
- W2093404230 hasConcept C86803240 @default.
- W2093404230 hasConcept C91965660 @default.
- W2093404230 hasConceptScore W2093404230C104317684 @default.
- W2093404230 hasConceptScore W2093404230C150903083 @default.
- W2093404230 hasConceptScore W2093404230C179998833 @default.
- W2093404230 hasConceptScore W2093404230C181199279 @default.
- W2093404230 hasConceptScore W2093404230C185592680 @default.
- W2093404230 hasConceptScore W2093404230C207001950 @default.
- W2093404230 hasConceptScore W2093404230C2777477808 @default.
- W2093404230 hasConceptScore W2093404230C2779554091 @default.
- W2093404230 hasConceptScore W2093404230C2781184954 @default.
- W2093404230 hasConceptScore W2093404230C2781259782 @default.
- W2093404230 hasConceptScore W2093404230C33288867 @default.
- W2093404230 hasConceptScore W2093404230C43617362 @default.
- W2093404230 hasConceptScore W2093404230C552990157 @default.
- W2093404230 hasConceptScore W2093404230C55493867 @default.
- W2093404230 hasConceptScore W2093404230C67705224 @default.
- W2093404230 hasConceptScore W2093404230C86803240 @default.
- W2093404230 hasConceptScore W2093404230C91965660 @default.
- W2093404230 hasIssue "1-2" @default.
- W2093404230 hasLocation W20934042301 @default.
- W2093404230 hasLocation W20934042302 @default.
- W2093404230 hasOpenAccess W2093404230 @default.
- W2093404230 hasPrimaryLocation W20934042301 @default.
- W2093404230 hasRelatedWork W1692906745 @default.
- W2093404230 hasRelatedWork W1929246383 @default.
- W2093404230 hasRelatedWork W1964948091 @default.
- W2093404230 hasRelatedWork W2057897655 @default.
- W2093404230 hasRelatedWork W2064650063 @default.
- W2093404230 hasRelatedWork W2070472590 @default.
- W2093404230 hasRelatedWork W2411160824 @default.
- W2093404230 hasRelatedWork W2415081720 @default.
- W2093404230 hasRelatedWork W2443128301 @default.
- W2093404230 hasRelatedWork W944700683 @default.
- W2093404230 hasVolume "831" @default.
- W2093404230 isParatext "false" @default.
- W2093404230 isRetracted "false" @default.
- W2093404230 magId "2093404230" @default.
- W2093404230 workType "article" @default.