FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093428785> ?p ?o ?g. }

• W2093428785 endingPage "1074" @default.
• W2093428785 startingPage "1067" @default.
• W2093428785 abstract "Background and aims Low birth weight affects 1 in every 7 babies born globally and can predict a lifetime of increased risk for adverse health outcomes, including cardiovascular disease, hypertension, obesity, diabetes, and metabolic syndrome. Maternal low protein diet during pregnancy and lactation is a well-characterized rat model for low birth weight and the subsequent increase in chronic disease risk. However, mice have been relatively understudied in this paradigm and represent a critical resource for investigating the underlying molecular mechanisms that link adverse early life experience and the development of chronic disease. Methods and results The present manuscript describes a mouse model of low birth weight (maternal consumption of low protein diet (8% protein) through pregnancy and lactation) and characterizes metabolic adaptations (food intake, locomotor activity, oxygen consumption, and glucose tolerance) in male and female offspring. At weaning, mice were maintained either on the control diet or a high fat diet. Notable sex differences were observed, with male mice from the low protein pregnancies showing increased food intake, hyperactivity and increased metabolic rate only when weaned to the high fat diet, while female mice consistently showed increased food intake and were hypometabolic, regardless of post-weaning diet. Conclusion These data identify offspring sex and post-weaning diet as critical variables in the metabolic adaptations to early life protein deficiency, and suggest that females may be more vulnerable to the adverse long-term health consequences of low birth weight" @default.
• W2093428785 created "2016-06-24" @default.
• W2093428785 creator A5003889936 @default.
• W2093428785 creator A5026490721 @default.
• W2093428785 creator A5055210218 @default.
• W2093428785 date "2012-12-01" @default.
• W2093428785 modified "2023-10-04" @default.
• W2093428785 title "Metabolic adaptations to early life protein restriction differ by offspring sex and post-weaning diet in the mouse" @default.
• W2093428785 cites W1523984548 @default.
• W2093428785 cites W1968775029 @default.
• W2093428785 cites W1993932990 @default.
• W2093428785 cites W2008710069 @default.
• W2093428785 cites W2010667681 @default.
• W2093428785 cites W2011484135 @default.
• W2093428785 cites W2033931500 @default.
• W2093428785 cites W2037310269 @default.
• W2093428785 cites W2042091448 @default.
• W2093428785 cites W2043033696 @default.
• W2093428785 cites W2061084753 @default.
• W2093428785 cites W2064757899 @default.
• W2093428785 cites W2067224371 @default.
• W2093428785 cites W2067941372 @default.
• W2093428785 cites W2069389301 @default.
• W2093428785 cites W2071654122 @default.
• W2093428785 cites W2072363990 @default.
• W2093428785 cites W2073795741 @default.
• W2093428785 cites W2083774373 @default.
• W2093428785 cites W2089457881 @default.
• W2093428785 cites W2102575366 @default.
• W2093428785 cites W2103049726 @default.
• W2093428785 cites W2108283346 @default.
• W2093428785 cites W2115116599 @default.
• W2093428785 cites W2126108743 @default.
• W2093428785 cites W2127056941 @default.
• W2093428785 cites W2139782987 @default.
• W2093428785 cites W2142455655 @default.
• W2093428785 cites W2144866168 @default.
• W2093428785 cites W2148879736 @default.
• W2093428785 cites W2335460664 @default.
• W2093428785 doi "https://doi.org/10.1016/j.numecd.2011.02.007" @default.
• W2093428785 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3183163" @default.
• W2093428785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21704502" @default.
• W2093428785 hasPublicationYear "2012" @default.
• W2093428785 type Work @default.
• W2093428785 sameAs 2093428785 @default.
• W2093428785 citedByCount "26" @default.
• W2093428785 countsByYear W20934287852013 @default.
• W2093428785 countsByYear W20934287852014 @default.
• W2093428785 countsByYear W20934287852015 @default.
• W2093428785 countsByYear W20934287852017 @default.
• W2093428785 countsByYear W20934287852018 @default.
• W2093428785 countsByYear W20934287852019 @default.
• W2093428785 countsByYear W20934287852020 @default.
• W2093428785 countsByYear W20934287852021 @default.
• W2093428785 countsByYear W20934287852022 @default.
• W2093428785 countsByYear W20934287852023 @default.
• W2093428785 crossrefType "journal-article" @default.
• W2093428785 hasAuthorship W2093428785A5003889936 @default.
• W2093428785 hasAuthorship W2093428785A5026490721 @default.
• W2093428785 hasAuthorship W2093428785A5055210218 @default.
• W2093428785 hasBestOaLocation W20934287852 @default.
• W2093428785 hasConcept C112672928 @default.
• W2093428785 hasConcept C126322002 @default.
• W2093428785 hasConcept C134018914 @default.
• W2093428785 hasConcept C2776659692 @default.
• W2093428785 hasConcept C2777180221 @default.
• W2093428785 hasConcept C2777661713 @default.
• W2093428785 hasConcept C2779083892 @default.
• W2093428785 hasConcept C2779234561 @default.
• W2093428785 hasConcept C2780655333 @default.
• W2093428785 hasConcept C42407357 @default.
• W2093428785 hasConcept C511355011 @default.
• W2093428785 hasConcept C54355233 @default.
• W2093428785 hasConcept C555293320 @default.
• W2093428785 hasConcept C66322754 @default.
• W2093428785 hasConcept C71924100 @default.
• W2093428785 hasConcept C86803240 @default.
• W2093428785 hasConceptScore W2093428785C112672928 @default.
• W2093428785 hasConceptScore W2093428785C126322002 @default.
• W2093428785 hasConceptScore W2093428785C134018914 @default.
• W2093428785 hasConceptScore W2093428785C2776659692 @default.
• W2093428785 hasConceptScore W2093428785C2777180221 @default.
• W2093428785 hasConceptScore W2093428785C2777661713 @default.
• W2093428785 hasConceptScore W2093428785C2779083892 @default.
• W2093428785 hasConceptScore W2093428785C2779234561 @default.
• W2093428785 hasConceptScore W2093428785C2780655333 @default.
• W2093428785 hasConceptScore W2093428785C42407357 @default.
• W2093428785 hasConceptScore W2093428785C511355011 @default.
• W2093428785 hasConceptScore W2093428785C54355233 @default.
• W2093428785 hasConceptScore W2093428785C555293320 @default.
• W2093428785 hasConceptScore W2093428785C66322754 @default.
• W2093428785 hasConceptScore W2093428785C71924100 @default.
• W2093428785 hasConceptScore W2093428785C86803240 @default.
• W2093428785 hasIssue "12" @default.
• W2093428785 hasLocation W20934287851 @default.
• W2093428785 hasLocation W20934287852 @default.
• W2093428785 hasLocation W20934287853 @default.
• W2093428785 hasLocation W20934287854 @default.

• next