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- W2093442803 endingPage "366" @default.
- W2093442803 startingPage "353" @default.
- W2093442803 abstract "Besides growth hormone, several pharmaceutical products have been investigated for efficacy and safety in increasing short term growth or adult height. Short-term treatment with testosterone esters in boys with constitutional delay of growth and puberty is efficacious in generating secondary sex characteristics and growth acceleration. The addition of oxandrolone to growth hormone (GH) in Turner syndrome has an additive effect on adult height gain. Treatment with GnRH analogs is the established treatment of central precocious puberty, and its addition to GH therapy appears effective in increasing adult height in GH deficient children, and possibly short children born SGA or with SHOX deficiency, who are still short at pubertal onset. Aromatase inhibitors appear effective in several rare disorders, but their value in increasing adult height in early pubertal boys with GH deficiency or idiopathic short stature is uncertain. A trial with a C-natriuretic peptide analog offers hope for children with achondroplasia." @default.
- W2093442803 created "2016-06-24" @default.
- W2093442803 creator A5054571302 @default.
- W2093442803 creator A5063096363 @default.
- W2093442803 date "2015-06-01" @default.
- W2093442803 modified "2023-09-27" @default.
- W2093442803 title "Novel approaches to short stature therapy" @default.
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