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- W2093467545 abstract "Standardized surgical wounds were evaluated in rats measuring water, sodium, potassium, chloride, and magnesium shifts over a period of sixty days. The water phase of development of the third fluid space in the wound was very rapid, being completed in five hours in this model. Sodium transfer into the wound was initially rapid, but continued for up to ten days, and correlated best with potassium loss. Correlation with water shifts was much less than anticipated. Magnesium tended to parallel potassium, and both began to replete after ten days as sodium content fell. The rapid transfer of water and sodium initially into a muscle wound was followed by dissociation of water and sodium flux, with water returning to control levels substantially before electrolyte restitution. Clinical implications of these observations are discussed." @default.
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- W2093467545 date "1971-04-01" @default.
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- W2093467545 title "Wound kinetics: Water and electrolyte changes from zero to sixty days in clean wounds" @default.
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- W2093467545 doi "https://doi.org/10.1016/0002-9610(71)90240-6" @default.
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