FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093471722> ?p ?o ?g. }

• W2093471722 endingPage "365" @default.
• W2093471722 startingPage "353" @default.
• W2093471722 abstract "Synonymous codons are neutral at the protein level, therefore natural selection at the protein level should have no effect on their frequencies. Synonymous codons, however, differ in their capacity to reduce the effects of errors: after mutation, certain codons keep on coding for the same amino acid or for amino acids with similar properties, while other synonymous codons produce very different amino acids. Therefore, the impact of errors on a coding sequence (genetic robustness) can be measured by analysing its codon usage. I analyse the codon usage of sequenced nuclear and cytoplasmic genomes and I show that there is an extensive variation in genetic robustness at the DNA sequence level, both among genomes and among genes of the same genome. I also show theoretically that robustness can be adaptive, that is natural selection may lead to a preference for codons that reduce the impact of errors. If selection occurs only among the mutants of a codon (e.g. among the progeny before the adult phase), however, the codons that are more sensitive to the effects of mutations may increase in frequency because they manage to get rid more easily of deleterious mutations. I also suggest other possible explanations for the evolution of genetic robustness at the codon level." @default.
• W2093471722 created "2016-06-24" @default.
• W2093471722 creator A5005001958 @default.
• W2093471722 date "2005-11-09" @default.
• W2093471722 modified "2023-10-10" @default.
• W2093471722 title "Genetic robustness and selection at the protein level for synonymous codons" @default.
• W2093471722 cites W1160445781 @default.
• W2093471722 cites W1607443343 @default.
• W2093471722 cites W1972732583 @default.
• W2093471722 cites W1977957322 @default.
• W2093471722 cites W1978595049 @default.
• W2093471722 cites W1988419621 @default.
• W2093471722 cites W1992289347 @default.
• W2093471722 cites W1994528559 @default.
• W2093471722 cites W2004146038 @default.
• W2093471722 cites W2004674004 @default.
• W2093471722 cites W2011505601 @default.
• W2093471722 cites W2020266144 @default.
• W2093471722 cites W2029941653 @default.
• W2093471722 cites W2033040997 @default.
• W2093471722 cites W2043592686 @default.
• W2093471722 cites W2058433720 @default.
• W2093471722 cites W2059075567 @default.
• W2093471722 cites W2073701242 @default.
• W2093471722 cites W2080664238 @default.
• W2093471722 cites W2082190159 @default.
• W2093471722 cites W2099599918 @default.
• W2093471722 cites W2102950230 @default.
• W2093471722 cites W2112269135 @default.
• W2093471722 cites W2126074998 @default.
• W2093471722 cites W2137389492 @default.
• W2093471722 cites W2147126179 @default.
• W2093471722 cites W2157613837 @default.
• W2093471722 cites W2159845019 @default.
• W2093471722 cites W2167485371 @default.
• W2093471722 cites W4235618707 @default.
• W2093471722 doi "https://doi.org/10.1111/j.1420-9101.2005.01029.x" @default.
• W2093471722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16599911" @default.
• W2093471722 hasPublicationYear "2005" @default.
• W2093471722 type Work @default.
• W2093471722 sameAs 2093471722 @default.
• W2093471722 citedByCount "23" @default.
• W2093471722 countsByYear W20934717222012 @default.
• W2093471722 countsByYear W20934717222013 @default.
• W2093471722 countsByYear W20934717222016 @default.
• W2093471722 countsByYear W20934717222017 @default.
• W2093471722 countsByYear W20934717222018 @default.
• W2093471722 countsByYear W20934717222020 @default.
• W2093471722 countsByYear W20934717222021 @default.
• W2093471722 crossrefType "journal-article" @default.
• W2093471722 hasAuthorship W2093471722A5005001958 @default.
• W2093471722 hasBestOaLocation W20934717222 @default.
• W2093471722 hasConcept C104317684 @default.
• W2093471722 hasConcept C10853874 @default.
• W2093471722 hasConcept C138025448 @default.
• W2093471722 hasConcept C141231307 @default.
• W2093471722 hasConcept C149129301 @default.
• W2093471722 hasConcept C154945302 @default.
• W2093471722 hasConcept C195491092 @default.
• W2093471722 hasConcept C41008148 @default.
• W2093471722 hasConcept C501734568 @default.
• W2093471722 hasConcept C515207424 @default.
• W2093471722 hasConcept C54355233 @default.
• W2093471722 hasConcept C63479239 @default.
• W2093471722 hasConcept C70721500 @default.
• W2093471722 hasConcept C7386963 @default.
• W2093471722 hasConcept C75268714 @default.
• W2093471722 hasConcept C75563809 @default.
• W2093471722 hasConcept C81917197 @default.
• W2093471722 hasConcept C86803240 @default.
• W2093471722 hasConcept C87253356 @default.
• W2093471722 hasConcept C91779695 @default.
• W2093471722 hasConceptScore W2093471722C104317684 @default.
• W2093471722 hasConceptScore W2093471722C10853874 @default.
• W2093471722 hasConceptScore W2093471722C138025448 @default.
• W2093471722 hasConceptScore W2093471722C141231307 @default.
• W2093471722 hasConceptScore W2093471722C149129301 @default.
• W2093471722 hasConceptScore W2093471722C154945302 @default.
• W2093471722 hasConceptScore W2093471722C195491092 @default.
• W2093471722 hasConceptScore W2093471722C41008148 @default.
• W2093471722 hasConceptScore W2093471722C501734568 @default.
• W2093471722 hasConceptScore W2093471722C515207424 @default.
• W2093471722 hasConceptScore W2093471722C54355233 @default.
• W2093471722 hasConceptScore W2093471722C63479239 @default.
• W2093471722 hasConceptScore W2093471722C70721500 @default.
• W2093471722 hasConceptScore W2093471722C7386963 @default.
• W2093471722 hasConceptScore W2093471722C75268714 @default.
• W2093471722 hasConceptScore W2093471722C75563809 @default.
• W2093471722 hasConceptScore W2093471722C81917197 @default.
• W2093471722 hasConceptScore W2093471722C86803240 @default.
• W2093471722 hasConceptScore W2093471722C87253356 @default.
• W2093471722 hasConceptScore W2093471722C91779695 @default.
• W2093471722 hasIssue "2" @default.
• W2093471722 hasLocation W20934717221 @default.
• W2093471722 hasLocation W20934717222 @default.
• W2093471722 hasLocation W20934717223 @default.
• W2093471722 hasOpenAccess W2093471722 @default.
• W2093471722 hasPrimaryLocation W20934717221 @default.

• next