FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093478280> ?p ?o ?g. }

• W2093478280 endingPage "3869" @default.
• W2093478280 startingPage "3864" @default.
• W2093478280 abstract "Febrifugine is an alkaloid isolated from Dichroa febrifuga as the active component against Plasmodium falciparum. Adverse side effects have precluded febrifugine as a potential clinical drug. As part of an ongoing malaria chemotherapy project, novel febrifugine analogues were designed and synthesized. Lower toxicity of these newly designed compounds was achieved by reducing or eliminating the tendency to form chemically reactive and toxic intermediates. New compounds possess excellent in vivo antimalarial activity and most of them become less toxic than the natural product febrifugine. Some of the compounds possess a therapeutic index over ten times superior to that of febrifugine and the commonly used antimalarial drug chloroquine. These compounds, as well as the underlying design rationale, may find usefulness in the discovery and development of new antimalarial drugs." @default.
• W2093478280 created "2016-06-24" @default.
• W2093478280 creator A5000911778 @default.
• W2093478280 creator A5029252485 @default.
• W2093478280 creator A5034604512 @default.
• W2093478280 creator A5035869703 @default.
• W2093478280 creator A5082400885 @default.
• W2093478280 creator A5090146247 @default.
• W2093478280 date "2010-09-01" @default.
• W2093478280 modified "2023-10-11" @default.
• W2093478280 title "Synthesis and evaluation of 4-quinazolinone compounds as potential antimalarial agents" @default.
• W2093478280 cites W1525031618 @default.
• W2093478280 cites W178765559 @default.
• W2093478280 cites W1969146976 @default.
• W2093478280 cites W1973783631 @default.
• W2093478280 cites W1975797305 @default.
• W2093478280 cites W1989774045 @default.
• W2093478280 cites W1998305107 @default.
• W2093478280 cites W2002176487 @default.
• W2093478280 cites W2008137254 @default.
• W2093478280 cites W2016962067 @default.
• W2093478280 cites W2036040407 @default.
• W2093478280 cites W2043043801 @default.
• W2093478280 cites W2044242984 @default.
• W2093478280 cites W2047031852 @default.
• W2093478280 cites W2054127150 @default.
• W2093478280 cites W2069958659 @default.
• W2093478280 cites W2071231030 @default.
• W2093478280 cites W2076003502 @default.
• W2093478280 cites W2105668259 @default.
• W2093478280 cites W2135461351 @default.
• W2093478280 cites W2148272620 @default.
• W2093478280 cites W2312227080 @default.
• W2093478280 cites W2315825939 @default.
• W2093478280 cites W2325225492 @default.
• W2093478280 cites W2444436131 @default.
• W2093478280 cites W2788073857 @default.
• W2093478280 cites W2950934323 @default.
• W2093478280 doi "https://doi.org/10.1016/j.ejmech.2010.05.040" @default.
• W2093478280 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2918702" @default.
• W2093478280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20538379" @default.
• W2093478280 hasPublicationYear "2010" @default.
• W2093478280 type Work @default.
• W2093478280 sameAs 2093478280 @default.
• W2093478280 citedByCount "69" @default.
• W2093478280 countsByYear W20934782802012 @default.
• W2093478280 countsByYear W20934782802013 @default.
• W2093478280 countsByYear W20934782802014 @default.
• W2093478280 countsByYear W20934782802015 @default.
• W2093478280 countsByYear W20934782802016 @default.
• W2093478280 countsByYear W20934782802017 @default.
• W2093478280 countsByYear W20934782802018 @default.
• W2093478280 countsByYear W20934782802019 @default.
• W2093478280 countsByYear W20934782802020 @default.
• W2093478280 countsByYear W20934782802021 @default.
• W2093478280 countsByYear W20934782802022 @default.
• W2093478280 countsByYear W20934782802023 @default.
• W2093478280 crossrefType "journal-article" @default.
• W2093478280 hasAuthorship W2093478280A5000911778 @default.
• W2093478280 hasAuthorship W2093478280A5029252485 @default.
• W2093478280 hasAuthorship W2093478280A5034604512 @default.
• W2093478280 hasAuthorship W2093478280A5035869703 @default.
• W2093478280 hasAuthorship W2093478280A5082400885 @default.
• W2093478280 hasAuthorship W2093478280A5090146247 @default.
• W2093478280 hasBestOaLocation W20934782802 @default.
• W2093478280 hasConcept C185592680 @default.
• W2093478280 hasConcept C203014093 @default.
• W2093478280 hasConcept C21951064 @default.
• W2093478280 hasConcept C2776120307 @default.
• W2093478280 hasConcept C2777162773 @default.
• W2093478280 hasConcept C2777425658 @default.
• W2093478280 hasConcept C2777667214 @default.
• W2093478280 hasConcept C2778048844 @default.
• W2093478280 hasConcept C2778371730 @default.
• W2093478280 hasConcept C2779396153 @default.
• W2093478280 hasConcept C2780035454 @default.
• W2093478280 hasConcept C2908859342 @default.
• W2093478280 hasConcept C71240020 @default.
• W2093478280 hasConcept C71924100 @default.
• W2093478280 hasConcept C98274493 @default.
• W2093478280 hasConceptScore W2093478280C185592680 @default.
• W2093478280 hasConceptScore W2093478280C203014093 @default.
• W2093478280 hasConceptScore W2093478280C21951064 @default.
• W2093478280 hasConceptScore W2093478280C2776120307 @default.
• W2093478280 hasConceptScore W2093478280C2777162773 @default.
• W2093478280 hasConceptScore W2093478280C2777425658 @default.
• W2093478280 hasConceptScore W2093478280C2777667214 @default.
• W2093478280 hasConceptScore W2093478280C2778048844 @default.
• W2093478280 hasConceptScore W2093478280C2778371730 @default.
• W2093478280 hasConceptScore W2093478280C2779396153 @default.
• W2093478280 hasConceptScore W2093478280C2780035454 @default.
• W2093478280 hasConceptScore W2093478280C2908859342 @default.
• W2093478280 hasConceptScore W2093478280C71240020 @default.
• W2093478280 hasConceptScore W2093478280C71924100 @default.
• W2093478280 hasConceptScore W2093478280C98274493 @default.
• W2093478280 hasIssue "9" @default.
• W2093478280 hasLocation W20934782801 @default.
• W2093478280 hasLocation W20934782802 @default.

• next