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- W2093521789 abstract "The menisci of the human knee joint are semi-lunar shaped discs located between the femoral condyles and the tibial plateaux. They have a role in lubrication, load bearing, shock absorption and joint stability [ 1 Brantigan O.C. Voshell A.F. The mechanics of the ligaments and menisci of the knee joint. J Bone Joint Surg (Am). 1941; 23: 44-66 Google Scholar , 10 Kurosawa H. Fukubayashi T. Nakajima H. Load-bearing mode of the knee joint: physical behaviour of the knee joint with or without menisci. Clin Orthop. 1980; 149: 283-290 PubMed Google Scholar , 16 Shrive N.G. O'Connor J.J. Goodfellow J.W. Load bearing in the knee joint. Clin Orthop. 1978; 131: 279-287 PubMed Google Scholar ] and if they are torn or excised then secondary osteo-arthritis will eventually develop [ [7] Fairbank T.J. Knee joint changes after meniscectomy. J Bone Joint Surg (Br). 1948; 30: 664-670 Google Scholar ]. Furthermore, with the vogue now for chondral autologous re-implantation techniques for re-surfacing traumatic defects, this would be contra-indicated if the menisci were absent. Consequently, current meniscal surgery aims at meniscal conservation by meniscal repair where possible [ 4 Cooper D.E. Arnoczky S.P. Warren R.F. Meniscal repair. Clin Sports Med. 1991; 10: 529-548 PubMed Google Scholar , 5 DeHaven K.E. Peripheral meniscus repair: an alternative to meniscectomy. J Bone Joint Surg (Br). 1981; 63: 463 Google Scholar , 12 Miller M.D. Ritchie J.R. Harner C.D. Meniscus surgery: indications for repair. Op Techn Sports Med. 1994; 2: 164-171 Abstract Full Text PDF Scopus (5) Google Scholar ]. Whole meniscal reconstruction using autograft tissue [ [11] Milachowski K.A. Weismeier K. Wirth C.J. Homologous meniscus transplantation. Experimental and clinical results. Int Orthop. 1989; 13: 1-11 Crossref PubMed Scopus (359) Google Scholar ] but mostly allograft tissue has been proposed and reported. Allograft meniscal reconstruction undoubtedly works [ [2] Cameron J.C. Saha S. Meniscal allograft transplantation for unicompartmental arthritis of the knee. Clin Orthop. 1997; 337: 164-171 Crossref PubMed Scopus (180) Google Scholar ], but there are many problems in connection with donor supply, methods of preservation [ 6 Fabbriciani C. Lucania L. Milano G. Panni A.S. Evangelisti M. Meniscal allografts: cryopreservation versus deep-frozen technique. An experimental study in goats. Knee Surg Sports Traumatol Arthrosc. 1997; 5: 124-134 Crossref PubMed Scopus (87) Google Scholar , 14 Pegg D. Personal communication. York University Google Scholar ] and risks of infection. With the recent emergence in the last decade of Tissue Engineering as a viable method [ [3] Cima L.G. Vacanti J.P. Vacanti C. Ingber D. Mooney D. Langer R. Tissue engineering by cell transplantation using degradable polymer substrates. J Biomech Eng. 1991; 113: 143-151 Crossref PubMed Scopus (525) Google Scholar ], it would seem reasonable to propose that meniscal generation by such means would be relatively easy." @default.
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- W2093521789 date "2003-03-01" @default.
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- W2093521789 title "Human meniscal chondrocyte culture and matrix infiltration with specific reference to meniscal generation" @default.
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- W2093521789 doi "https://doi.org/10.1016/s0968-0160(02)00043-1" @default.
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