FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093535469> ?p ?o ?g. }

• W2093535469 endingPage "277" @default.
• W2093535469 startingPage "266" @default.
• W2093535469 abstract "Certain environmental parameters are accessible to cells only indirectly and require an encoding step for cells to retrieve the relevant information. A prominent example is the phenomenon of quorum sensing by microorganisms, where information about cell density is encoded by means of secreted signaling molecules. The mapping of cell density to signal molecule concentration and the corresponding network modules involved have been at least partially characterized in many bacteria, and vary markedly between different systems. In this study, we investigate theoretically how differences in signal transport, signal modification, and site of signal detection shape the encoding function and affect the sensitivity and the noise characteristics of the cell-density-encoding process. We find that different modules are capable of implementing both fairly basic as well as more complex encoding schemes, whose qualitative characteristics vary with cell density and are linked to network architecture, providing the basis for a hierarchical classification scheme. We exploit the tight relationship between encoding behavior and network architecture to constrain the network topology of partially characterized natural systems, and verify one such prediction by showing experimentally that Vibrio harveyi is capable of importing Autoinducer 2. The framework developed in this research can serve not only to guide reverse engineering of natural systems but also to stimulate the design of synthetic systems and generally facilitate a better understanding of the complexities arising in the quorum-sensing process because of variations in the physical organization of the encoder network module." @default.
• W2093535469 created "2016-06-24" @default.
• W2093535469 creator A5016795461 @default.
• W2093535469 creator A5042759458 @default.
• W2093535469 creator A5067159735 @default.
• W2093535469 creator A5069189535 @default.
• W2093535469 date "2014-07-01" @default.
• W2093535469 modified "2023-10-10" @default.
• W2093535469 title "A Modular View of the Diversity of Cell-Density-Encoding Schemes in Bacterial Quorum-Sensing Systems" @default.
• W2093535469 cites W1502461125 @default.
• W2093535469 cites W1603665563 @default.
• W2093535469 cites W1632889752 @default.
• W2093535469 cites W1896976965 @default.
• W2093535469 cites W1972224836 @default.
• W2093535469 cites W1977624796 @default.
• W2093535469 cites W1979211796 @default.
• W2093535469 cites W1982310237 @default.
• W2093535469 cites W1999851893 @default.
• W2093535469 cites W2000798486 @default.
• W2093535469 cites W2021862571 @default.
• W2093535469 cites W2027576577 @default.
• W2093535469 cites W2030764181 @default.
• W2093535469 cites W2032256798 @default.
• W2093535469 cites W2033296687 @default.
• W2093535469 cites W2039582130 @default.
• W2093535469 cites W2042321087 @default.
• W2093535469 cites W2044286308 @default.
• W2093535469 cites W2053744250 @default.
• W2093535469 cites W2056932987 @default.
• W2093535469 cites W2063137442 @default.
• W2093535469 cites W2065833295 @default.
• W2093535469 cites W2066503782 @default.
• W2093535469 cites W2073233593 @default.
• W2093535469 cites W2074701664 @default.
• W2093535469 cites W2076055471 @default.
• W2093535469 cites W2078734278 @default.
• W2093535469 cites W2080357982 @default.
• W2093535469 cites W2085176138 @default.
• W2093535469 cites W2090280615 @default.
• W2093535469 cites W2096223900 @default.
• W2093535469 cites W2099090468 @default.
• W2093535469 cites W2100460169 @default.
• W2093535469 cites W2102653059 @default.
• W2093535469 cites W2111173827 @default.
• W2093535469 cites W2114591302 @default.
• W2093535469 cites W2115130110 @default.
• W2093535469 cites W2115335630 @default.
• W2093535469 cites W2118521369 @default.
• W2093535469 cites W2124152757 @default.
• W2093535469 cites W2124327234 @default.
• W2093535469 cites W2126055663 @default.
• W2093535469 cites W2126922170 @default.
• W2093535469 cites W2127347791 @default.
• W2093535469 cites W2131869707 @default.
• W2093535469 cites W2136294927 @default.
• W2093535469 cites W2137088684 @default.
• W2093535469 cites W2138377634 @default.
• W2093535469 cites W2139667048 @default.
• W2093535469 cites W2141564052 @default.
• W2093535469 cites W2144069064 @default.
• W2093535469 cites W2148879985 @default.
• W2093535469 cites W2149311070 @default.
• W2093535469 cites W2161466984 @default.
• W2093535469 cites W2166662833 @default.
• W2093535469 cites W2166807076 @default.
• W2093535469 cites W2169937805 @default.
• W2093535469 cites W4229932570 @default.
• W2093535469 doi "https://doi.org/10.1016/j.bpj.2014.05.031" @default.
• W2093535469 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4119280" @default.
• W2093535469 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24988360" @default.
• W2093535469 hasPublicationYear "2014" @default.
• W2093535469 type Work @default.
• W2093535469 sameAs 2093535469 @default.
• W2093535469 citedByCount "23" @default.
• W2093535469 countsByYear W20935354692014 @default.
• W2093535469 countsByYear W20935354692015 @default.
• W2093535469 countsByYear W20935354692016 @default.
• W2093535469 countsByYear W20935354692017 @default.
• W2093535469 countsByYear W20935354692018 @default.
• W2093535469 countsByYear W20935354692019 @default.
• W2093535469 countsByYear W20935354692020 @default.
• W2093535469 countsByYear W20935354692021 @default.
• W2093535469 countsByYear W20935354692022 @default.
• W2093535469 crossrefType "journal-article" @default.
• W2093535469 hasAuthorship W2093535469A5016795461 @default.
• W2093535469 hasAuthorship W2093535469A5042759458 @default.
• W2093535469 hasAuthorship W2093535469A5067159735 @default.
• W2093535469 hasAuthorship W2093535469A5069189535 @default.
• W2093535469 hasBestOaLocation W20935354691 @default.
• W2093535469 hasConcept C101468663 @default.
• W2093535469 hasConcept C104317684 @default.
• W2093535469 hasConcept C111919701 @default.
• W2093535469 hasConcept C118687296 @default.
• W2093535469 hasConcept C119599485 @default.
• W2093535469 hasConcept C120314980 @default.
• W2093535469 hasConcept C125411270 @default.
• W2093535469 hasConcept C127413603 @default.
• W2093535469 hasConcept C14036430 @default.

• next