FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093539106> ?p ?o ?g. }

• W2093539106 endingPage "736" @default.
• W2093539106 startingPage "731" @default.
• W2093539106 abstract "Background: Ameloblastoma is an odontogenic benign tumor characterized by local invasiveness and most of its local recurrences clinically result from local invasion. This study used matrix metalloproteinase-2 (MMP-2) inhibitor I (MMP-2I) to investigate the role played by MMP-2 activity in the local invasiveness of ameloblastoma. Methods: The cells and xenografts of ameloblastoma were treated with MMP-2I and treatment group were compared with the control group. In vitro, the invasive activity of tumor cells was assayed in transwell cell culture chamber. Gelatinolytic activity of gelatinases and MMP-2/tissue inhibitor of matrix metalloproteinase (TIMP-2) protein expression was detected using gelatin zymography and flow cytometry. The cell viability and adhesion were evaluated using methyl thiazol tetrazolium. In vivo, bilateral subrenal capsule xenograft transplantation of ameloblastoma was performed in 10 nude mice and the invasion of ameloblastoma into the renal parenchyma was observed. Results: Active-MMP-2 of conditioned media was significantly lower in treatment group than in the control group. Accordingly, potential of in vitro cell invasion, adhesion and in vivo tumor invasion were also significantly lower in the treatment group than in the control group. Conclusions: Inhibitor of MMP-2 activity suppressed the local invasive capability of ameloblastoma by decreasing MMP-2 activity. MMP-2 activity is in relation with invasive capacity of ameloblastoma." @default.
• W2093539106 created "2016-06-24" @default.
• W2093539106 creator A5014071783 @default.
• W2093539106 creator A5032588771 @default.
• W2093539106 creator A5037575658 @default.
• W2093539106 creator A5037740110 @default.
• W2093539106 creator A5045334809 @default.
• W2093539106 creator A5046881277 @default.
• W2093539106 creator A5055174519 @default.
• W2093539106 creator A5084835562 @default.
• W2093539106 date "2009-10-01" @default.
• W2093539106 modified "2023-10-07" @default.
• W2093539106 title "Inhibition of ameloblastoma invasion<i>in vitro</i>and<i>in vivo</i>by inhibitor of metalloproteinase-2 activity" @default.
• W2093539106 cites W1997559135 @default.
• W2093539106 cites W2005707246 @default.
• W2093539106 cites W2011134969 @default.
• W2093539106 cites W2023786025 @default.
• W2093539106 cites W2035330461 @default.
• W2093539106 cites W2083746931 @default.
• W2093539106 cites W2113056676 @default.
• W2093539106 cites W2114587896 @default.
• W2093539106 cites W2147471000 @default.
• W2093539106 cites W2151138082 @default.
• W2093539106 cites W2183737084 @default.
• W2093539106 cites W4230628886 @default.
• W2093539106 cites W4251856366 @default.
• W2093539106 cites W4312567304 @default.
• W2093539106 doi "https://doi.org/10.1111/j.1600-0714.2009.00771.x" @default.
• W2093539106 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19473446" @default.
• W2093539106 hasPublicationYear "2009" @default.
• W2093539106 type Work @default.
• W2093539106 sameAs 2093539106 @default.
• W2093539106 citedByCount "13" @default.
• W2093539106 countsByYear W20935391062012 @default.
• W2093539106 countsByYear W20935391062013 @default.
• W2093539106 countsByYear W20935391062014 @default.
• W2093539106 countsByYear W20935391062016 @default.
• W2093539106 countsByYear W20935391062017 @default.
• W2093539106 countsByYear W20935391062018 @default.
• W2093539106 countsByYear W20935391062020 @default.
• W2093539106 countsByYear W20935391062021 @default.
• W2093539106 countsByYear W20935391062022 @default.
• W2093539106 crossrefType "journal-article" @default.
• W2093539106 hasAuthorship W2093539106A5014071783 @default.
• W2093539106 hasAuthorship W2093539106A5032588771 @default.
• W2093539106 hasAuthorship W2093539106A5037575658 @default.
• W2093539106 hasAuthorship W2093539106A5037740110 @default.
• W2093539106 hasAuthorship W2093539106A5045334809 @default.
• W2093539106 hasAuthorship W2093539106A5046881277 @default.
• W2093539106 hasAuthorship W2093539106A5055174519 @default.
• W2093539106 hasAuthorship W2093539106A5084835562 @default.
• W2093539106 hasConcept C105702510 @default.
• W2093539106 hasConcept C109523444 @default.
• W2093539106 hasConcept C122246415 @default.
• W2093539106 hasConcept C126322002 @default.
• W2093539106 hasConcept C142724271 @default.
• W2093539106 hasConcept C150903083 @default.
• W2093539106 hasConcept C177430391 @default.
• W2093539106 hasConcept C185592680 @default.
• W2093539106 hasConcept C207001950 @default.
• W2093539106 hasConcept C2775876115 @default.
• W2093539106 hasConcept C2911091166 @default.
• W2093539106 hasConcept C502942594 @default.
• W2093539106 hasConcept C71924100 @default.
• W2093539106 hasConcept C86803240 @default.
• W2093539106 hasConceptScore W2093539106C105702510 @default.
• W2093539106 hasConceptScore W2093539106C109523444 @default.
• W2093539106 hasConceptScore W2093539106C122246415 @default.
• W2093539106 hasConceptScore W2093539106C126322002 @default.
• W2093539106 hasConceptScore W2093539106C142724271 @default.
• W2093539106 hasConceptScore W2093539106C150903083 @default.
• W2093539106 hasConceptScore W2093539106C177430391 @default.
• W2093539106 hasConceptScore W2093539106C185592680 @default.
• W2093539106 hasConceptScore W2093539106C207001950 @default.
• W2093539106 hasConceptScore W2093539106C2775876115 @default.
• W2093539106 hasConceptScore W2093539106C2911091166 @default.
• W2093539106 hasConceptScore W2093539106C502942594 @default.
• W2093539106 hasConceptScore W2093539106C71924100 @default.
• W2093539106 hasConceptScore W2093539106C86803240 @default.
• W2093539106 hasIssue "9" @default.
• W2093539106 hasLocation W20935391061 @default.
• W2093539106 hasLocation W20935391062 @default.
• W2093539106 hasOpenAccess W2093539106 @default.
• W2093539106 hasPrimaryLocation W20935391061 @default.
• W2093539106 hasRelatedWork W1972933415 @default.
• W2093539106 hasRelatedWork W1980902990 @default.
• W2093539106 hasRelatedWork W2028067028 @default.
• W2093539106 hasRelatedWork W2042303973 @default.
• W2093539106 hasRelatedWork W2087087143 @default.
• W2093539106 hasRelatedWork W2117980967 @default.
• W2093539106 hasRelatedWork W2383320628 @default.
• W2093539106 hasRelatedWork W2421372801 @default.
• W2093539106 hasRelatedWork W2680992019 @default.
• W2093539106 hasRelatedWork W2782857268 @default.
• W2093539106 hasVolume "38" @default.
• W2093539106 isParatext "false" @default.
• W2093539106 isRetracted "false" @default.
• W2093539106 magId "2093539106" @default.

• next