FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093595105> ?p ?o ?g. }

• W2093595105 endingPage "pdb.emo107" @default.
• W2093595105 startingPage "pdb.emo107" @default.
• W2093595105 abstract "INTRODUCTIONThe perpetual darkness of caves has two important consequences for permanent inhabitants. First, eyes and pigmentation lose their primary functions. Second, in the absence of photosynthesis, food is rare. For these reasons, cave-adapted species typically have reduced eyes and pigmentation and increased or more efficient metabolisms. Additionally, other senses are usually augmented to compensate for the loss of vision. Identifying the genetic bases underlying these phenotypic changes will enhance our understanding of the specific pathways involved in control of these phenotypes and, in general, the evolutionary process. Unfortunately, the genetics of most cave animals cannot be studied because they are not easily bred. Blind Mexican tetras, Astyanax mexicanus, are the valuable exception to this rule because fish from the various cave populations are fully interfertile with one another and with eyed sister forms still living in nearby surface streams. Hybrids between surface and cave forms permit genetic analysis of their differences, and study of the pure forms as well as of hybrids allows study of their developmental differences. Quantitative trait loci (QTL) analysis has already identified some specific genes responsible for differences between cave and surface forms as well as other likely candidates; more will be added in the future. This system is a valuable addition to the array of existing models for the study of developmental and evolutionary genetics because cave populations are repositories of numerous naturally occurring mutations affecting development of the eyes and other senses, pigmentation, bone structure, metamerism, and metabolism. These alleles have been prescreened by natural selection for high viability, which simplifies their study. In contrast, new alleles obtained through mutagenesis in other model species are typically burdened with lower viability." @default.
• W2093595105 created "2016-06-24" @default.
• W2093595105 creator A5023226419 @default.
• W2093595105 date "2008-11-01" @default.
• W2093595105 modified "2023-09-26" @default.
• W2093595105 title "<i>Astyanax mexicanus</i>, the Blind Mexican Cave Fish: A Model for Studies in Development and Morphology: Figure 1." @default.
• W2093595105 cites W1897850981 @default.
• W2093595105 cites W1981705330 @default.
• W2093595105 cites W1990257951 @default.
• W2093595105 cites W1996279502 @default.
• W2093595105 cites W2043168088 @default.
• W2093595105 cites W2060513403 @default.
• W2093595105 cites W2060886811 @default.
• W2093595105 cites W2072727594 @default.
• W2093595105 cites W2074626235 @default.
• W2093595105 cites W2078002075 @default.
• W2093595105 cites W2106946808 @default.
• W2093595105 cites W2147343083 @default.
• W2093595105 doi "https://doi.org/10.1101/pdb.emo107" @default.
• W2093595105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21356710" @default.
• W2093595105 hasPublicationYear "2008" @default.
• W2093595105 type Work @default.
• W2093595105 sameAs 2093595105 @default.
• W2093595105 citedByCount "22" @default.
• W2093595105 countsByYear W20935951052012 @default.
• W2093595105 countsByYear W20935951052014 @default.
• W2093595105 countsByYear W20935951052016 @default.
• W2093595105 countsByYear W20935951052017 @default.
• W2093595105 countsByYear W20935951052018 @default.
• W2093595105 countsByYear W20935951052019 @default.
• W2093595105 countsByYear W20935951052020 @default.
• W2093595105 countsByYear W20935951052021 @default.
• W2093595105 countsByYear W20935951052023 @default.
• W2093595105 crossrefType "journal-article" @default.
• W2093595105 hasAuthorship W2093595105A5023226419 @default.
• W2093595105 hasConcept C104317684 @default.
• W2093595105 hasConcept C106934330 @default.
• W2093595105 hasConcept C127716648 @default.
• W2093595105 hasConcept C144024400 @default.
• W2093595105 hasConcept C149923435 @default.
• W2093595105 hasConcept C154945302 @default.
• W2093595105 hasConcept C167683757 @default.
• W2093595105 hasConcept C171878925 @default.
• W2093595105 hasConcept C18832751 @default.
• W2093595105 hasConcept C18903297 @default.
• W2093595105 hasConcept C199360897 @default.
• W2093595105 hasConcept C2908647359 @default.
• W2093595105 hasConcept C41008148 @default.
• W2093595105 hasConcept C48189365 @default.
• W2093595105 hasConcept C54355233 @default.
• W2093595105 hasConcept C59822182 @default.
• W2093595105 hasConcept C75268714 @default.
• W2093595105 hasConcept C78458016 @default.
• W2093595105 hasConcept C81917197 @default.
• W2093595105 hasConcept C86803240 @default.
• W2093595105 hasConcept C90132467 @default.
• W2093595105 hasConcept C90856448 @default.
• W2093595105 hasConceptScore W2093595105C104317684 @default.
• W2093595105 hasConceptScore W2093595105C106934330 @default.
• W2093595105 hasConceptScore W2093595105C127716648 @default.
• W2093595105 hasConceptScore W2093595105C144024400 @default.
• W2093595105 hasConceptScore W2093595105C149923435 @default.
• W2093595105 hasConceptScore W2093595105C154945302 @default.
• W2093595105 hasConceptScore W2093595105C167683757 @default.
• W2093595105 hasConceptScore W2093595105C171878925 @default.
• W2093595105 hasConceptScore W2093595105C18832751 @default.
• W2093595105 hasConceptScore W2093595105C18903297 @default.
• W2093595105 hasConceptScore W2093595105C199360897 @default.
• W2093595105 hasConceptScore W2093595105C2908647359 @default.
• W2093595105 hasConceptScore W2093595105C41008148 @default.
• W2093595105 hasConceptScore W2093595105C48189365 @default.
• W2093595105 hasConceptScore W2093595105C54355233 @default.
• W2093595105 hasConceptScore W2093595105C59822182 @default.
• W2093595105 hasConceptScore W2093595105C75268714 @default.
• W2093595105 hasConceptScore W2093595105C78458016 @default.
• W2093595105 hasConceptScore W2093595105C81917197 @default.
• W2093595105 hasConceptScore W2093595105C86803240 @default.
• W2093595105 hasConceptScore W2093595105C90132467 @default.
• W2093595105 hasConceptScore W2093595105C90856448 @default.
• W2093595105 hasIssue "11" @default.
• W2093595105 hasLocation W20935951051 @default.
• W2093595105 hasLocation W20935951052 @default.
• W2093595105 hasOpenAccess W2093595105 @default.
• W2093595105 hasPrimaryLocation W20935951051 @default.
• W2093595105 hasRelatedWork W1890342101 @default.
• W2093595105 hasRelatedWork W2078459261 @default.
• W2093595105 hasRelatedWork W2475566521 @default.
• W2093595105 hasRelatedWork W2498164133 @default.
• W2093595105 hasRelatedWork W2563063294 @default.
• W2093595105 hasRelatedWork W4206303876 @default.
• W2093595105 hasRelatedWork W4230519926 @default.
• W2093595105 hasRelatedWork W4243130659 @default.
• W2093595105 hasRelatedWork W4246166768 @default.
• W2093595105 hasRelatedWork W75950068 @default.
• W2093595105 hasVolume "2008" @default.
• W2093595105 isParatext "false" @default.
• W2093595105 isRetracted "false" @default.
• W2093595105 magId "2093595105" @default.

• next