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• W2093600309 abstract "I demonstrate that the U snRNAs of human cells are hetero geneous in sequence. Polyacrylamide gel and RNase T fingerprint analyses of U RNAs isolated from a variety of human cultured cells, including HeLa. 293. K562 and NT2/D. show tha minor variants of the human U RNA (hUa) comprise between 5% and 15% of the total U RNAs in these established cell lines. The patterns of variants are cell line specific, suggesting that expression of these minor species of hUa RNAs reflect polymorphisms of the hUa true genes rather than existence of an additional class of human embryonic U genes. Also, the hUa variants described here are not the products of previously identified human U Class I pseudogenes." @default.
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• W2093600309 date "1988-07-11" @default.
• W2093600309 modified "2023-09-26" @default.
• W2093600309 title "Heterogeneity of human U snRNAs" @default.
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• W2093600309 doi "https://doi.org/10.1093/nar/16.13.5813" @default.
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