FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093640585> ?p ?o ?g. }

• W2093640585 endingPage "383" @default.
• W2093640585 startingPage "373" @default.
• W2093640585 abstract "Infectious diseases, caused by protozoa, such as malaria, sleeping sickness, Chagas' disease or leishmaniasis, are a global threat. The increase in the number of affected individuals and the rapid spread of drug-resistant strains call for specific novel strategies to combat human pathogenic parasites. In the search for novel drug targets, transport proteins for nutrients and metabolites of the parasite-host interface are getting into focus. The present review summarizes and discusses the currently available results on protozoan aquaporins. Various genes coding for aquaporin water and solute channels have been identified in the protozoan genomes and they are probable elements of the parasite's cell membrane. Phylogenetic analysis reveals that individual aquaporin genes are of bacterial or plant origin. So far, six protozoan aquaporins have been cloned and functionally characterized. Typically, these are bifunctional channels and pass water at intermediate to high rates as well as uncharged solutes. In the present review, amino acid compositions of the individual pore entries are compared and permeability properties are attributed to specific protein features. Furthermore, possible physiological roles in osmotic protection and metabolism are discussed. Finally, the potential of protozoan aquaporins for use as a target or entry pathway for chemotherapeutic compounds is reviewed." @default.
• W2093640585 created "2016-06-24" @default.
• W2093640585 creator A5005788321 @default.
• W2093640585 date "2005-06-01" @default.
• W2093640585 modified "2023-10-12" @default.
• W2093640585 title "Aquaporins from pathogenic protozoan parasites: structure, function and potential for chemotherapy" @default.
• W2093640585 cites W1504082382 @default.
• W2093640585 cites W1533645179 @default.
• W2093640585 cites W1559236087 @default.
• W2093640585 cites W1805989424 @default.
• W2093640585 cites W1947778485 @default.
• W2093640585 cites W1957028641 @default.
• W2093640585 cites W1964314854 @default.
• W2093640585 cites W1964343317 @default.
• W2093640585 cites W1971909283 @default.
• W2093640585 cites W1994179682 @default.
• W2093640585 cites W1996386189 @default.
• W2093640585 cites W1999165043 @default.
• W2093640585 cites W2009749225 @default.
• W2093640585 cites W2010182284 @default.
• W2093640585 cites W2016638691 @default.
• W2093640585 cites W2019851585 @default.
• W2093640585 cites W2024399685 @default.
• W2093640585 cites W2025148115 @default.
• W2093640585 cites W2028075573 @default.
• W2093640585 cites W2033503608 @default.
• W2093640585 cites W2034998098 @default.
• W2093640585 cites W2040438092 @default.
• W2093640585 cites W2043585539 @default.
• W2093640585 cites W2046391188 @default.
• W2093640585 cites W2057582709 @default.
• W2093640585 cites W2057726245 @default.
• W2093640585 cites W2061032623 @default.
• W2093640585 cites W2073985048 @default.
• W2093640585 cites W2078936885 @default.
• W2093640585 cites W2092002806 @default.
• W2093640585 cites W2092398899 @default.
• W2093640585 cites W2105546584 @default.
• W2093640585 cites W2120981128 @default.
• W2093640585 cites W2136288803 @default.
• W2093640585 cites W2150864606 @default.
• W2093640585 cites W2168080849 @default.
• W2093640585 cites W2399186596 @default.
• W2093640585 cites W4210954078 @default.
• W2093640585 cites W61051756 @default.
• W2093640585 doi "https://doi.org/10.1042/bc20040095" @default.
• W2093640585 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15901246" @default.
• W2093640585 hasPublicationYear "2005" @default.
• W2093640585 type Work @default.
• W2093640585 sameAs 2093640585 @default.
• W2093640585 citedByCount "84" @default.
• W2093640585 countsByYear W20936405852012 @default.
• W2093640585 countsByYear W20936405852013 @default.
• W2093640585 countsByYear W20936405852014 @default.
• W2093640585 countsByYear W20936405852015 @default.
• W2093640585 countsByYear W20936405852016 @default.
• W2093640585 countsByYear W20936405852017 @default.
• W2093640585 countsByYear W20936405852018 @default.
• W2093640585 countsByYear W20936405852019 @default.
• W2093640585 countsByYear W20936405852020 @default.
• W2093640585 countsByYear W20936405852021 @default.
• W2093640585 countsByYear W20936405852022 @default.
• W2093640585 countsByYear W20936405852023 @default.
• W2093640585 crossrefType "journal-article" @default.
• W2093640585 hasAuthorship W2093640585A5005788321 @default.
• W2093640585 hasConcept C104317684 @default.
• W2093640585 hasConcept C141231307 @default.
• W2093640585 hasConcept C154280991 @default.
• W2093640585 hasConcept C2778566189 @default.
• W2093640585 hasConcept C54355233 @default.
• W2093640585 hasConcept C70721500 @default.
• W2093640585 hasConcept C86803240 @default.
• W2093640585 hasConcept C89423630 @default.
• W2093640585 hasConcept C95444343 @default.
• W2093640585 hasConceptScore W2093640585C104317684 @default.
• W2093640585 hasConceptScore W2093640585C141231307 @default.
• W2093640585 hasConceptScore W2093640585C154280991 @default.
• W2093640585 hasConceptScore W2093640585C2778566189 @default.
• W2093640585 hasConceptScore W2093640585C54355233 @default.
• W2093640585 hasConceptScore W2093640585C70721500 @default.
• W2093640585 hasConceptScore W2093640585C86803240 @default.
• W2093640585 hasConceptScore W2093640585C89423630 @default.
• W2093640585 hasConceptScore W2093640585C95444343 @default.
• W2093640585 hasIssue "6" @default.
• W2093640585 hasLocation W20936405851 @default.
• W2093640585 hasLocation W20936405852 @default.
• W2093640585 hasOpenAccess W2093640585 @default.
• W2093640585 hasPrimaryLocation W20936405851 @default.
• W2093640585 hasRelatedWork W1836342204 @default.
• W2093640585 hasRelatedWork W1986819841 @default.
• W2093640585 hasRelatedWork W202868969 @default.
• W2093640585 hasRelatedWork W2046014422 @default.
• W2093640585 hasRelatedWork W2104223187 @default.
• W2093640585 hasRelatedWork W2113681449 @default.
• W2093640585 hasRelatedWork W2154009044 @default.
• W2093640585 hasRelatedWork W2467703106 @default.
• W2093640585 hasRelatedWork W3142543453 @default.
• W2093640585 hasRelatedWork W812052363 @default.

• next