FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093644145> ?p ?o ?g. }

• W2093644145 endingPage "446" @default.
• W2093644145 startingPage "439" @default.
• W2093644145 abstract "In trangenerational epigenetic inheritance, phenotypic information not encoded in DNA sequence is transmitted across generations. In germline-dependent mode, memory of environmental exposure in parental generation is transmitted through gametes, leading to appearance of phenotypes in the unexposed future generations. The memory is considered to be encoded in epigenetic factors like DNA methylation, histone modifications and regulatory RNAs. Environmental exposure may cause epigenetic modifications in the germline either directly or indirectly through primarily affecting the soma. The latter possibility is most intriguing because it contradicts the established dogma that hereditary information flows only from germline to soma, not in reverse. As such, identification of the factor(s) mediating soma to germline information transfer in transgenerational epigenetic inheritance would be pathbreaking. Regulatory RNAs and hormone have previously been implicated or proposed to play a role in soma to germline communication in epigenetic inheritance. This review examines the recent examples of gametogenic transgenerational inheritance in plants and animals in order to assess if evidence of regulatory RNAs and hormones as mediators of information transfer is supported. Overall, direct evidence for both mobile regulatory RNAs and hormones is found to exist in plants. In animals, although involvement of mobile RNAs seems imminent, direct evidence of RNA-mediated soma to germline information transfer in transgenerational epigenetic inheritance is yet to be obtained. Direct evidence is also lacking for hormones in animals. However, detailed examination of recently reported examples of transgenerational inheritance reveals circumstantial evidence supporting a role of hormones in information transmission." @default.
• W2093644145 created "2016-06-24" @default.
• W2093644145 creator A5035937945 @default.
• W2093644145 date "2013-12-01" @default.
• W2093644145 modified "2023-09-26" @default.
• W2093644145 title "Transgenerational epigenetic inheritance: Focus on soma to germline information transfer" @default.
• W2093644145 cites W1487412251 @default.
• W2093644145 cites W1523984548 @default.
• W2093644145 cites W1526516695 @default.
• W2093644145 cites W1647075334 @default.
• W2093644145 cites W1806462425 @default.
• W2093644145 cites W182314314 @default.
• W2093644145 cites W1963466636 @default.
• W2093644145 cites W1964050348 @default.
• W2093644145 cites W1964388814 @default.
• W2093644145 cites W1965574594 @default.
• W2093644145 cites W1967609877 @default.
• W2093644145 cites W1971387586 @default.
• W2093644145 cites W1971708895 @default.
• W2093644145 cites W1972170949 @default.
• W2093644145 cites W1972618119 @default.
• W2093644145 cites W1972647460 @default.
• W2093644145 cites W1973960846 @default.
• W2093644145 cites W1974236422 @default.
• W2093644145 cites W1974690602 @default.
• W2093644145 cites W1974717708 @default.
• W2093644145 cites W1976626368 @default.
• W2093644145 cites W1977082276 @default.
• W2093644145 cites W1979990445 @default.
• W2093644145 cites W1981025527 @default.
• W2093644145 cites W1983796420 @default.
• W2093644145 cites W1983920520 @default.
• W2093644145 cites W1984611853 @default.
• W2093644145 cites W1985769321 @default.
• W2093644145 cites W1987104387 @default.
• W2093644145 cites W1990777401 @default.
• W2093644145 cites W1993350141 @default.
• W2093644145 cites W1994208378 @default.
• W2093644145 cites W1994962498 @default.
• W2093644145 cites W1995049218 @default.
• W2093644145 cites W1995087873 @default.
• W2093644145 cites W1996284070 @default.
• W2093644145 cites W1997796525 @default.
• W2093644145 cites W1997970568 @default.
• W2093644145 cites W1998502291 @default.
• W2093644145 cites W2000548593 @default.
• W2093644145 cites W2001070286 @default.
• W2093644145 cites W2006732621 @default.
• W2093644145 cites W2007463943 @default.
• W2093644145 cites W2008764123 @default.
• W2093644145 cites W2009866838 @default.
• W2093644145 cites W2010313286 @default.
• W2093644145 cites W2010691380 @default.
• W2093644145 cites W2013736504 @default.
• W2093644145 cites W2015305713 @default.
• W2093644145 cites W2015574605 @default.
• W2093644145 cites W2015681884 @default.
• W2093644145 cites W2018295108 @default.
• W2093644145 cites W2019858243 @default.
• W2093644145 cites W2022386905 @default.
• W2093644145 cites W2022976083 @default.
• W2093644145 cites W2023331548 @default.
• W2093644145 cites W2029741050 @default.
• W2093644145 cites W2030423376 @default.
• W2093644145 cites W2032640887 @default.
• W2093644145 cites W2032663499 @default.
• W2093644145 cites W2032879466 @default.
• W2093644145 cites W2035208962 @default.
• W2093644145 cites W2036566096 @default.
• W2093644145 cites W2036598382 @default.
• W2093644145 cites W2036693641 @default.
• W2093644145 cites W2038237188 @default.
• W2093644145 cites W2040115176 @default.
• W2093644145 cites W2042275520 @default.
• W2093644145 cites W2044542770 @default.
• W2093644145 cites W2047896588 @default.
• W2093644145 cites W2052041575 @default.
• W2093644145 cites W2053640510 @default.
• W2093644145 cites W2055237453 @default.
• W2093644145 cites W2056182559 @default.
• W2093644145 cites W2058470179 @default.
• W2093644145 cites W2059632047 @default.
• W2093644145 cites W2060797201 @default.
• W2093644145 cites W2060860407 @default.
• W2093644145 cites W2064155145 @default.
• W2093644145 cites W2065351507 @default.
• W2093644145 cites W2065542901 @default.
• W2093644145 cites W2065704233 @default.
• W2093644145 cites W2066566245 @default.
• W2093644145 cites W2070366764 @default.
• W2093644145 cites W2071213636 @default.
• W2093644145 cites W2071461607 @default.
• W2093644145 cites W2073174869 @default.
• W2093644145 cites W2074137164 @default.
• W2093644145 cites W2074370653 @default.
• W2093644145 cites W2075331723 @default.
• W2093644145 cites W2076122447 @default.
• W2093644145 cites W2077906468 @default.

• next