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- W2093670304 abstract "The complexities of the protective immune response to Histoplasma capsulatum remain poorly understood. It is clear that an interaction between antigen-reactive T cells and macrophages is essential for successful resolution of infection. The primary focus in our laboratory is to identify the antigens from this fungus that stimulate T cells to mediate growth inhibition of H. capsulatum. We describe herein the results of studies that centered on the identification of two antigens that trigger T-cell proliferation and can confer protective immunity. These antigens potentially can be used to generate a vaccine against this pathogenic fungus. Key words: histoplasmosis, T cells, antigens, protective immunity, HIS-62." @default.
- W2093670304 created "2016-06-24" @default.
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- W2093670304 date "1995-12-31" @default.
- W2093670304 modified "2023-09-27" @default.
- W2093670304 title "Immunity in histoplasmosis: identification of protective immunogens from Histoplasma capsulatum" @default.
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- W2093670304 doi "https://doi.org/10.1139/b95-375" @default.
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