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• W2093676592 abstract "FOXM1 is a transcription factor required for a wide spectrum of essential biological functions, including DNA damage repair, cell proliferation, cell cycle progression, cell renewal, cell differentiation and tissue homeostasis. Recent evidence suggests that FOXM1 also has a role in many aspects of the DNA damage response. Accordingly, FOXM1 drives the transcription of genes for DNA damage sensors, mediators, signal transducers and effectors. As a result of these functions, it plays an integral part in maintaining the integrity of the genome and so is key to the propagation of accurate genetic information to the next generation. Preserving the genetic code is a vital means of suppressing cancer and other genetic diseases. Conversely, FOXM1 is also a potent oncogenic factor that is essential for cancer initiation, progression and drug resistance. An enhanced FOXM1 DNA damage repair gene expression network can confer resistance to genotoxic agents. Developing a thorough understanding of the regulation and function of FOXM1 in DNA damage response will improve the diagnosis and treatment of diseases including cancer, neurodegenerative conditions and immunodeficiency disorders. It will also benefit cancer patients with acquired genotoxic agent resistance." @default.
• W2093676592 created "2016-06-24" @default.
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• W2093676592 date "2014-11-01" @default.
• W2093676592 modified "2023-09-26" @default.
• W2093676592 title "FOXM1: An emerging master regulator of DNA damage response and genotoxic agent resistance" @default.
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• W2093676592 cites W1928552653 @default.
• W2093676592 cites W1961026612 @default.
• W2093676592 cites W1963634341 @default.
• W2093676592 cites W1969037652 @default.
• W2093676592 cites W1969711650 @default.
• W2093676592 cites W1972926597 @default.
• W2093676592 cites W1983432011 @default.
• W2093676592 cites W1985647633 @default.
• W2093676592 cites W1987090100 @default.
• W2093676592 cites W1988876917 @default.
• W2093676592 cites W1989931997 @default.
• W2093676592 cites W1993203583 @default.
• W2093676592 cites W1993491981 @default.
• W2093676592 cites W1994564000 @default.
• W2093676592 cites W1997393527 @default.
• W2093676592 cites W2002512110 @default.
• W2093676592 cites W2003601710 @default.
• W2093676592 cites W2008511245 @default.
• W2093676592 cites W2014574284 @default.
• W2093676592 cites W2014756186 @default.
• W2093676592 cites W2018708635 @default.
• W2093676592 cites W2019305724 @default.
• W2093676592 cites W2020717634 @default.
• W2093676592 cites W2024711136 @default.
• W2093676592 cites W2027653913 @default.
• W2093676592 cites W2028748220 @default.
• W2093676592 cites W2031203839 @default.
• W2093676592 cites W2033172828 @default.
• W2093676592 cites W2043895957 @default.
• W2093676592 cites W2054394510 @default.
• W2093676592 cites W2059030377 @default.
• W2093676592 cites W2060551076 @default.
• W2093676592 cites W2064215138 @default.
• W2093676592 cites W2065697119 @default.
• W2093676592 cites W2067265742 @default.
• W2093676592 cites W2068261932 @default.
• W2093676592 cites W2073285188 @default.
• W2093676592 cites W2073467950 @default.
• W2093676592 cites W2073567125 @default.
• W2093676592 cites W2077560715 @default.
• W2093676592 cites W2077892030 @default.
• W2093676592 cites W2081161468 @default.
• W2093676592 cites W2082641730 @default.
• W2093676592 cites W2084089807 @default.
• W2093676592 cites W2092435713 @default.
• W2093676592 cites W2093447167 @default.
• W2093676592 cites W2097124161 @default.
• W2093676592 cites W2097906998 @default.
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• W2093676592 cites W2123549011 @default.
• W2093676592 cites W2123696077 @default.
• W2093676592 cites W2124006755 @default.
• W2093676592 cites W2124616973 @default.
• W2093676592 cites W2132920733 @default.
• W2093676592 cites W2133836709 @default.
• W2093676592 cites W2134051389 @default.
• W2093676592 cites W2134071049 @default.
• W2093676592 cites W2135212986 @default.
• W2093676592 cites W2135630561 @default.
• W2093676592 cites W2138440511 @default.
• W2093676592 cites W2138897067 @default.
• W2093676592 cites W2145200068 @default.
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• W2093676592 cites W2148172964 @default.
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• W2093676592 doi "https://doi.org/10.1016/j.bbagrm.2014.09.016" @default.
• W2093676592 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4316173" @default.
• W2093676592 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25287128" @default.
• W2093676592 hasPublicationYear "2014" @default.
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